Protein Alignment pb and Hoxd8

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_032302.2
• Gene: Hoxd8 / 15437
• MGIID: 96209
• Length: 289
• Species: Mus musculus
• Alignment Length: 273
• Identity: 80/273 - (29%)
• Similarity: 107/273 - (39%)
• Gaps: 80/273 - (29%)

  Fly    36 PVGGCGGAGVVG-GVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGG 99
            |..||||.|..| |........|.|....|..||.|.. ......|.|               ||
Mouse    76 PPPGCGGGGGPGPGQDYFHAGAGSPTAAYQAAPPPPHP-PPPPPPPPC---------------GG 124

  Fly   100 F-INSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYP-----VGVVPQTPDG 158
            . .:.:|  |:|..:.:.:...|.|......:              |.||     .|.:.:.||.
Mouse   125 IACHGEP--AKFYGYDNLQRQPIFTTQQEAEL--------------VQYPDCKSSSGNIGEDPDH 173

  Fly   159 MD--SVPE--YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHF 219
            ::  |.|.  :|||:.:....:                      ||.|..|:..|.|||||||.|
Mouse   174 LNQSSSPSQMFPWMRPQAAPGR----------------------RRGRQTYSRFQTLELEKEFLF 216

  Fly   220 NKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSL-------KGDDDQS 277
            |.||.|.||||::.:|.|||||||:||||||||.|:        |:|||..       |..|.:.
Mouse   217 NPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKK--------ENNKDKFPASRPEAKDGDPKK 273

  Fly   278 DSNSNSKKSCQGC 290
            :.:...:...:||
Mouse   274 EVSGLEEDGAEGC 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	37/55 (67%)
Hoxd8	NP_032302.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..125		17/64 (27%)
		COG5576	139..272	CDD:227863	57/176 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..184		5/21 (24%)
		Antp-type hexapeptide	183..188		2/4 (50%)
		Homeodomain	196..252	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..289		8/43 (19%)