Protein Alignment pb and Hoxc13

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034594.1
• Gene: Hoxc13 / 15422
• MGIID: 99560
• Length: 328
• Species: Mus musculus
• Alignment Length: 313
• Identity: 78/313 - (24%)
• Similarity: 113/313 - (36%)
• Gaps: 110/313 - (35%)

  Fly    38 GGCGGAGVVGGVGGVGVSVGQPG-----IGQQGVPP-------VPSVLMVNKMTPNCDKRSADTA 90
            ||.||.|..||.|| |.|...||     .|..|..|       :|..::.....|
Mouse    29 GGGGGGGGAGGAGG-GCSGASPGKAPSMDGLGGSCPASHCRDLLPHPVLARPPAP---------- 82

  Fly    91 YWMTASEGGFINSQPSMAEFLNHLSPESPK--------IGTPVGSGAIGGVGVNVNVNV------ 141
              :.|.:|......|:.........|.:|.        .|.|.| |:..|..::.|||:
Mouse    83 --LGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFG-GSYYGCRLSHNVNLQQKPCA 144

  Fly   142 -GVGVGYP------------------------------------VGVVPQTPDGMDSVPE----- 164
             ..|..||                                    |.|||    |:...||
Mouse   145 YHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVP----GISGHPEPRHDA 205

  Fly   165 ------YP-------WMKEKKTSRKSSNNNNQGDNSITEFVP--------ENGLPRRLRTAYTNT 208
                  |.       |..:...|::.|.:.:...:...:.||        ..|  |:.|..||..
Mouse   206 LIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRG--RKKRVPYTKV 268

  Fly   209 QLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKT 261
            ||.|||||:..:|::.:.:|..|:|:.:|:||||.:||||||:|.|: .:||:
Mouse   269 QLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK-VVSKS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
Hoxc13	NP_034594.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..48		11/19 (58%)
		HoxA13_N	52..166	CDD:463521	21/126 (17%)
		Homeodomain	259..310	CDD:459649	24/50 (48%)