Protein Alignment pb and Hoxc12

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034593.1
• Gene: Hoxc12 / 15421
• MGIID: 96194
• Length: 280
• Species: Mus musculus
• Alignment Length: 268
• Identity: 72/268 - (26%)
• Similarity: 99/268 - (36%)
• Gaps: 66/268 - (24%)

  Fly     3 EVCSSLDTTSMGTQIKSESP------LNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGI 61
            |.|:......:|:.:....|      |..::...|....|....||.|:.....|     .:||.
Mouse    59 EPCNGYPQPYLGSPVSLNPPFGRTCELARVEDSKGYYREPCAEGGGGGLKREERG-----REPGA 118

  Fly    62 GQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINS-----QPSMAEFLNHLSPESPKI 121
            |     |..::|.:....|    .:....|..|||.||...|     .|...:.|     ||...
Mouse   119 G-----PGAALLQLEPSGP----PALGFKYDYTASGGGGDGSTGPPHDPPSCQSL-----ESDSS 169

  Fly   122 GTPVGSGAIGGVGVNVNVNVGVGVGYPVGVV-PQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGD 185
            .:.:..|           |.....|.|..:| |..|.|..|....||......|||.
Mouse   170 SSLLNEG-----------NKSASAGDPGSLVSPLNPGGGLSASGAPWYPIHSRSRKK-------- 215

  Fly   186 NSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRR 250
                            |..|:..||.|||.||..|:::.|.||.|::..|:|:::|||:||||||
Mouse   216 ----------------RKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRR 264

  Fly   251 MKHKRQTL 258
            ||.||..|
Mouse   265 MKKKRLLL 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
Hoxc12	NP_034593.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..212		33/146 (23%)
		Homeodomain	213..269	CDD:459649	29/79 (37%)