Protein Alignment pb and Hoxa3

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034582.1
• Gene: Hoxa3 / 15400
• MGIID: 96175
• Length: 443
• Species: Mus musculus
• Alignment Length: 738
• Identity: 157/738 - (21%)
• Similarity: 210/738 - (28%)
• Gaps: 363/738 - (49%)

  Fly     5 CSSLDTTSMG----TQIKSESPLNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQ-- 63
            ||.....|.|    |...||:.|..|   :|..|.|                      ||:|:
Mouse    51 CSLQSPASAGGHPKTHELSEACLRTL---SGPPSQP----------------------PGLGEPP 90

  Fly    64 ------QGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIG 122
                  |..||.|.........|.....:......::..:..  ||.|:.|.     :.:||.:.
Mouse    91 LPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSA--NSNPTPAS-----TAKSPLLN 148

  Fly   123 TPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKE------KKTSRKSSNNN 181
            :|.       ||..:                           :|||||      :|||..||..:
Mouse   149 SPT-------VGKQI---------------------------FPWMKESRQNTKQKTSGSSSGES 179

  Fly   182 NQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWF 246
            ..||.|    .|.....:|.|||||:.||:|||||||||:|||||||:|:|..|:|||||:|:||
Mouse   180 CAGDKS----PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWF 240

  Fly   247 QNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNT 311
            ||||||:|:       |:..|..|.....||.|.|              .:|
Mouse   241 QNRRMKYKK-------DQKGKGMLTSSGGQSPSRS--------------PVP------------- 271

  Fly   312 PSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKK 376
                   |.||
Mouse   272 -------PGAG------------------------------------------------------ 275

  Fly   377 KDDGQVIKKEAVSTSSKASPFGYENSTPSLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIAT 441
                                 ||.||..|||        ::|...|.|
Mouse   276 ---------------------GYLNSMHSLV--------NSVPYEPQS----------------- 294

  Fly   442 PTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQLHPQQQQLPQQQPQDYYGKYDIEFAA 506
            |.|.|....|       |.|..|..||:             |.....|...||..|.........
Mouse   295 PPPFSKPPQG-------AYGLPPASYPA-------------PLPSCAPPPPPQKRYTAAGSGAGG 339

  Fly   507 SPHHNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQNDHFYYNYNDTNGTPYLNHQQQHHHHAQH 571
            :|.::||     .||                          ...|.:.|||:|
Mouse   340 TPDYDPH-----AHG--------------------------LQGNGSYGTPHL------------ 361

  Fly   572 HQQQQHHQNHVADFEGPVNGPSNFNNGAYYDNMSFQQQAQAHQHQTVVFQQQQPHQPAAINHQHM 636
                              .|...|..|:|.:.||                    :........|:
Mouse   362 ------------------QGSPVFVGGSYVEPMS--------------------NSGPLFGLTHL 388

  Fly   637 HHLGNGETYSALGLQMENCEGYNNFGAAGTGGGYYEAGQQPPIPATHGHGHHPHHVQVPAQAHAP 701
            .|    .|.:|:           ::|  |||          |:.:.|.||..|..   |...:..
Mouse   389 PH----TTSAAM-----------DYG--GTG----------PLGSGHHHGPGPGE---PHPTYTD 423

  Fly   702 IHAHHNSAAIPGGVGVGPPPSHI 724
            :.|||.|   .|.:...|..:|:
Mouse   424 LTAHHPS---QGRIQEAPKLTHL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	57/111 (51%)
		Homeobox	202..254	CDD:278475	40/51 (78%)
Hoxa3	NP_034582.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..151		18/108 (17%)
		Antp-type hexapeptide	156..161		2/31 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..197		10/37 (27%)
		COG5576	<182..309	CDD:227863	73/278 (26%)
		Homeobox	196..249	CDD:365835	40/52 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	248..354		41/297 (14%)
		DUF4074	378..441	CDD:372548	20/95 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..443		14/57 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810