Protein Alignment pb and Hoxa2

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Alignment Length: 344
• Identity: 126/344 - (36%)
• Similarity: 162/344 - (47%)
• Gaps: 67/344 - (19%)

  Fly    97 EGGFINSQPSMAEFLNHLSP-----ESPKIGT----------PVGSGAIGGVGVNVNVNVGVGVG 146
            |.||||||||:||.|....|     :|..|.|          |.....|..:....:...|.|||
Mouse     8 EIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGVG 72

  Fly   147 -----YPVGV-VPQTPDGMDSVPEYPWMKEKKTSRK--------SSNNNNQGDNSITEFVP-ENG 196
                 .|.|. ....|.|....||||||||||.::|        |:.....|.....|... ..|
Mouse    73 GRPKSSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADGSGG 137

  Fly   197 LPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKT 261
            ..||||||||||||||||||||||||||||||:||||.|||||||||||||||||||||||..|.
Mouse   138 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKE 202

  Fly   262 DDEDN------KDSLKGDDDQSD--------SNSNSKKSCQGCELPSDDIPDSTSNSRGHNNN-- 310
            :....      :||.|.::|:.:        |.|.:....:|.....:.:....: ..|||.:
Mouse   203 NQNSEGKFKNLEDSDKVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQA-PNGHNGDSQ 266

  Fly   311 ----TPSATN---------NNPSAGNL--TPNSSLETGISSNLMGSTTVSA---SNVISADSSVA 357
                :|..:|         .:|:..|.  |...:...|::::...:..|.:   .||.|.||.:.
Mouse   267 TFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEAIEVPSLQDFNVFSTDSCLQ 331

  Fly   358 SSVSLDEDIEES--SPIKV 374
            .|.:|...:..|  ||:.:
Mouse   332 LSDALSPSLPGSLDSPVDI 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	71/120 (59%)
		Homeobox	202..254	CDD:278475	49/51 (96%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		10/46 (22%)
		Antp-type hexapeptide	96..101		4/4 (100%)
		Homeobox	143..195	CDD:278475	49/51 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		10/30 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5885
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		otm42860
orthoMCL	1	0.900	-	-		OOG6_110172
Panther	1	1.100	-	-	O	PTHR45664
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6877
SonicParanoid	1	1.000	-	-		X2356
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.800