Protein Alignment pb and Mnx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_064328.2
• Gene: Mnx1 / 15285
• MGIID: 109160
• Length: 404
• Species: Mus musculus
• Alignment Length: 478
• Identity: 119/478 - (24%)
• Similarity: 161/478 - (33%)
• Gaps: 148/478 - (30%)

  Fly     6 SSLDTTSMGTQIKSESPLNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVP 70
            ||..|.:.|.::::|||..|..:......||..|..||      ||.|.:.|.||.......|
Mouse    63 SSEATAAPGDRLRAESPSPPRLLAAHCALLPKPGFLGA------GGGGGAAGGPGTPHHHAHP-- 119

  Fly    71 SVLMVNKMTPNCDKRSADTAYWMTASEGGF-INSQPSMAEFLNHLSPESPKIGTPVGS-GAIGGV 133
                        ...:|..|....|:.||. :...|..|:....|..::...|.||.| .|....
Mouse   120 ------------GAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYSYSAAAAA 172

  Fly   134 GVNVNVNVGVGVGYP--VGVVPQTPD-----GMDSVPEYPWMKEKKTSR---KSSNNNNQGDNSI 188
            ......:..:...||  .|..|..|.     |..:.....|::......   |..:.::|..:::
Mouse   173 AALAGQHPALSYSYPQVQGAHPAHPADPIKLGASTFQLDQWLRASTAGMILPKMPDFSSQAQSNL 237

  Fly   189 TEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKH 253
            .      |..||.|||:|:.||||||.:|..||||.||:|.|:|.||.|||.|||:||||||||.
Mouse   238 L------GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKW 296

  Fly   254 KRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNN 318
            ||...:|.......:..||
Mouse   297 KRSKKAKEQAAQEAEKQKG---------------------------------------------- 315

  Fly   319 PSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVI 383
              .|..|.....|......|||..       :|.|.  ||...| .|:.:|.|      |:
Mouse   316 --GGGGTGKGGSEEKTEEELMGPP-------VSGDK--ASGRRL-RDLRDSDP------DE---- 358

  Fly   384 KKEAVSTSSKASPFGYENSTPSLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDS 448
                                        |.|.....|.|.|...|       |:|.:     ||.
Mouse   359 ----------------------------DEDDEEEDNFPYSNGAG-------AHAAS-----SDC 383

  Fly   449 NSGNGSGGGPAGGYFPGYYPSPK 471
            :|.:.|.....||  ||:.|.|:
Mouse   384 SSEDDSPPPRLGG--PGHQPLPQ 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	38/55 (69%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..80		6/16 (38%)
		Homeodomain	242..298	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..404		35/214 (16%)