DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and Gsx1

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	NP_032204.1	Gene:	Gsx1 / 14842	MGIID:	95842	Length:	261	Species:	Mus musculus

Alignment Length:	267	Identity:	80/267 - (29%)
Similarity:	119/267 - (44%)	Gaps:	64/267 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 QGVPP------VPSVLMVNKMTPN-CDKRSAD----TAYWMTASEGGFINSQPSMAEFLNHLSPE 117
            :|.||      ||....::.::|. |..|.|.    ....:|||:   ::..|. ...|..|...
Mouse    22 EGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQ---LHGPPG-PPALPLLKAS 82

  Fly   118 SPKIGTPVGSGAIGGV-GVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKK---TSRKSS 178
            .|..|:......:|.. .|:..|..|.........:.||        .||....::   .|..||
Mouse    83 FPPFGSQYCHAPLGRQHSVSPGVAHGPAAAAAAAALYQT--------SYPLPDPRQFHCISVDSS 139

  Fly   179 NNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVK 243
            :|.          :|.:   :|:|||:|:|||||||:||..|.||.|.||||||..|:|:|:|||
Mouse   140 SNQ----------LPSS---KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVK 191

  Fly   244 VWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSC-QGCELPS----------DDI 297
            :||||||:|||::.             ||.:.:..:.:.:.... |||:..|          |::
Mouse   192 IWFQNRRVKHKKEG-------------KGSNHRGGAGAGAGGGAPQGCKCSSLSSAKCSEDDDEL 243

  Fly   298 PDSTSNS 304
            |.|.|:|
Mouse   244 PMSPSSS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	46/108 (43%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	36/51 (71%)
Gsx1	NP_032204.1	SNAG domain. /evidence=ECO:0000250	1..20
		Homeobox	150..203	CDD:395001	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..261		13/63 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810