Protein Alignment pb and NKX2-6

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 120
• Identity: 40/120 - (33%)
• Similarity: 57/120 - (47%)
• Gaps: 18/120 - (15%)

  Fly   142 GVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYT 206
            |:....|:|       |...|||          |...|:.:......:| .|:....|:.|..::
Human    94 GLNAASPLG-------GGTRVPE----------RGVGNSGDSVRGGRSE-QPKARQRRKPRVLFS 140

  Fly   207 NTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKT 261
            ..|:|.||:.|...:||..|.|..:|::|.||..|||:||||||.|.|||...|:
Human   141 QAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKS 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	25/55 (45%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		12/58 (21%)
		Homeodomain	133..189	CDD:459649	25/55 (45%)