Protein Alignment pb and Cdx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 247
• Identity: 68/247 - (27%)
• Similarity: 93/247 - (37%)
• Gaps: 76/247 - (30%)

  Fly    92 WMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSG------AIGGVGVNVNVNVGVGVGYPVG 150
            |..|...|...|..|.|.......|:...:..|.|.|      ::|..|
Mouse    72 WAAAYGPGPTASAASPAPLAFGPPPDFSPVPAPPGPGPGILAQSLGAPG---------------- 120

  Fly   151 VVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEK 215
             .|.:|......| |.||:.   |..::.....|.....:         :.|..||:.|.|||||
Mouse   121 -APSSPGAPRRTP-YEWMRR---SVAAAGGGGSGKTRTKD---------KYRVVYTDHQRLELEK 171

  Fly   216 EFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSN 280
            |||:::|:...|:.|:||:|.|||||||:||||||.|.::
Mouse   172 EFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERK------------------------- 211

  Fly   281 SNSKKSCQGCELPSDDIP---DSTSNSRGHNNNTPSATNNNPSAGNLTPNSS 329
            .|.||..|...||...:|   |.|.        |||    .|..|:|.|.::
Mouse   212 VNKKKQQQQQPLPPTQLPLPLDGTP--------TPS----GPPLGSLCPTNA 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	32/55 (58%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		20/100 (20%)
		Caudal_act	13..140	CDD:461413	18/88 (20%)
		Homeodomain	156..211	CDD:459649	32/54 (59%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		12/20 (60%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		9/10 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		16/80 (20%)