Protein Alignment pb and Alx4

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_031468.1
• Gene: Alx4 / 11695
• MGIID: 108359
• Length: 399
• Species: Mus musculus
• Alignment Length: 437
• Identity: 95/437 - (21%)
• Similarity: 149/437 - (34%)
• Gaps: 101/437 - (23%)

  Fly     3 EVCSSLDTTSMGTQIKSESPLNPLQVQTGQTSLPVGGCGG----------AGVVGGVGGVGVSVG 57
            |.|.|...:.........||::    |:.:.|.|..|..|          ||..|...|...|..
Mouse     4 ETCVSYCESPAAAMDAYYSPVS----QSREGSSPFRGFPGGDKFGTTFLSAGAKGQGFGDAKSRA 64

  Fly    58 QPGIGQQGV-PPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKI 121
            :.|.|||.: .|:.|                     .:.:.|.|...||.........:|.:|..
Mouse    65 RYGAGQQDLAAPLES---------------------SSGARGSFNKFQPQPPTPQPPPAPPAPPA 108

  Fly   122 GTPVGSGAI------------GGVGVNVNVNVGV-----GVGYPVGVVPQTPDGMDSVPEYPWMK 169
            ...:..||.            |..|.|..:.|..     .:|.|.......|.|||:    .::.
Mouse   109 HLYLQRGACKTPPDGSLKLQEGSGGHNAALQVPCYAKESNLGEPELPPDSEPVGMDN----SYLS 169

  Fly   170 EKKTSRKSSNNNNQGD----NSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIE 230
            .|:|..|...:....:    ...|:.....|..||.||.:|:.||.||||.|....|.....|.:
Mouse   170 VKETGAKGPQDRASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQ 234

  Fly   231 IAASLDLTERQVKVWFQNRRMK-HKRQTLSKTDD----------------EDNKDSLKGDDDQSD 278
            :|...||||.:|:|||||||.| .||:...:...                .:|...:     |:.
Mouse   235 LAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQI-----QNP 294

  Fly   279 S---NSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMG 340
            |   |:.:......|.:|.|.:|...|         |.|  :.|.:|..:.:..|....:.:.:|
Mouse   295 SWIGNNGAASPVPACVVPCDPVPACMS---------PHA--HPPGSGASSVSDFLSVSGAGSHVG 348

  Fly   341 STTV----SASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVI 383
            .|.:    .|:.:....:....:...|......:.:::|.|:....|
Mouse   349 QTHMGSLFGAAGISPGLNGYEMNGEPDRKTSSIAALRMKAKEHSAAI 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/56 (50%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..133		14/85 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..206		7/34 (21%)
		Homeodomain	203..259	CDD:459649	28/55 (51%)
		OAR	375..393	CDD:461067	3/17 (18%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	379..392		2/12 (17%)