Protein Alignment pb and VAX1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001106175.1
• Gene: VAX1 / 11023
• HGNCID: 12660
• Length: 334
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 78/320 - (24%)
• Similarity: 116/320 - (36%)
• Gaps: 97/320 - (30%)

  Fly   178 SNNNNQGD-------------NSITEFVPENGL----PRRLRTAYTNTQLLELEKEFHFNKYLCR 225
            |.:|:..|             .||.|.:...||    |:|.||::|..||..||.||...:|:..
Human    63 SKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVG 127

  Fly   226 PRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSC--- 287
            ..|.|:|..|:|:|.||||||||||.|.|:        :..|||     :.....|.:..:|
Human   128 RERTELARQLNLSETQVKVWFQNRRTKQKK--------DQGKDS-----ELRSVVSETAATCSVL 179

  Fly   288 ----QGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASN 348
                ||..|....:|...         .|.||.                .:.|.|.|.:..:...
Human   180 RLLEQGRLLSPPGLPALL---------PPCATG----------------ALGSALRGPSLPALGA 219

  Fly   349 VISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFG--------------- 398
            ..:|.|:.|::.:.......:||            ...||..:....|.|
Human   220 GAAAGSAAAAAAAAPGPAGAASP------------HPPAVGGAPGPGPAGPGGLHAGAPAAGHSL 272

  Fly   399 YENSTPSLVSFRRDSDASAVGNAPTSKA---VGKKRFQSAANAIATP-TPLSDSNSGNGS 454
            :....|||:.    |.||.:.:||.:.|   .|..:..||....::. .|.|.:|:..|:
Human   273 FSLPVPSLLG----SVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGA 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
VAX1	NP_001106175.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		COG5576	66..184	CDD:227863	42/130 (32%)
		Homeodomain	101..157	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..263		6/40 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..334		4/15 (27%)