Protein Alignment pb and CDX2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 68/275 - (24%)
• Similarity: 101/275 - (36%)
• Gaps: 71/275 - (25%)

  Fly    92 WMTASEGGFINSQPSMAEFLN----------------------HLSPESPKIGTPVGSGAIGGVG 134
            |...:.||...:..::|..||                      |..|..|.......||.:
Human    77 WNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLL---- 137

  Fly   135 VNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPR 199
              ..:|.|...........|...|........||  :|.:::|     .|..::|.  |.:.:..
Human   138 --QTLNPGPPGPAATAAAEQLSPGGQRRNLCEWM--RKPAQQS-----LGSQALTS--PSSTVKT 191

  Fly   200 R----LRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSK 260
            |    .|..||:.|.||||||||:::|:...|:.|:||:|.|:|||||:||||||.|.::
Human   192 RTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERK----- 251

  Fly   261 TDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLT 325
                .||..|:....|....            |....|.......|...:.|..         |:
Human   252 ----INKKKLQQQQQQQPPQ------------PPPPPPQPPQPQPGPLRSVPEP---------LS 291

  Fly   326 PNSSLETGISSNLMG 340
            |.|||:..:..::.|
Human   292 PVSSLQASVPGSVPG 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	32/59 (54%)
CDX2	XP_011533177.1	Caudal_act	13..179	CDD:461413	19/114 (17%)
		Homeodomain	196..251	CDD:459649	31/54 (57%)