Protein Alignment pb and Hoxa2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_036713.2
• Gene: Hoxa2 / 103690123
• RGDID: 11468112
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 123/347 - (35%)
• Similarity: 160/347 - (46%)
• Gaps: 73/347 - (21%)

  Fly    97 EGGFINSQPSMAEFLNHLSP-----ESPKIGT----------PVGSGAIGGVGVNVNVNVGVGVG 146
            |.||||||||:||.|....|     :|..|.|          |.....|..:....:.....|.|
  Rat     8 EIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRQSAGAG 72

  Fly   147 YPVGVVPQTPDGMD---------SVPEYPWMKEKKTSRK--------SSNNNNQGDNSITEFVP- 193
               |....:|.|..         ..||||||||||.::|        |:.....|.....|...
  Rat    73 ---GRPKSSPAGSRGSPVPARALQPPEYPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADG 134

  Fly   194 ENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTL 258
            ..|..||||||||||||||||||||||||||||||:||||.|||||||||||||||||||||||.
  Rat   135 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 199

  Fly   259 SKTDDEDN------KDSLKGDDDQSD--------SNSNSKKSCQGCELPSDDIPDSTSNSRGHNN 309
            .|.:....      :||.|.::|:.:        |.|.:....:|.....:.:....: ..|||.
  Rat   200 CKENQNSEGKFKNLEDSDKVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQA-PNGHNG 263

  Fly   310 N------TPSATN---------NNPSAGNL--TPNSSLETGISSNLMGSTTVSA---SNVISADS 354
            :      :|..:|         .:|:..|.  |...:...|::::...:..|.:   .||.|.||
  Rat   264 DSQTFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEALEVPSLQDFNVFSTDS 328

  Fly   355 SVASSVSLDEDIEES--SPIKV 374
            .:..|.:|...:..|  ||:.:
  Rat   329 CLQLSDALSPSLPGSLDSPVDI 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	53/55 (96%)
Hoxa2	NP_036713.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..96		7/56 (13%)
		Antp-type hexapeptide	96..101		4/4 (100%)
		Homeodomain	140..196	CDD:459649	53/55 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		10/30 (33%)