Protein Alignment pb and pitx3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_002935807.2
• Gene: pitx3 / 100496690
• XenbaseID: XB-GENE-486162
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 260
• Identity: 78/260 - (30%)
• Similarity: 115/260 - (44%)
• Gaps: 50/260 - (19%)

  Fly   169 KEKKTSRKSSNNNNQGDNSITEFVPENGL----PRRLRTAYTNTQLLELEKEFHFNKYLCRPRRI 229
            :|...:.||..|.....|      ||:|.    .||.||.:|:.||.|||..|..|:|.....|.
 Frog    33 QEHSDTEKSQQNQTDDSN------PEDGTLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTRE 91

  Fly   230 EIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNS-KKSCQGCELP 293
            |||...:|||.:|:|||:|||.|.:::       |.|:        |::...|| .....|...|
 Frog    92 EIAVWTNLTEARVRVWFKNRRAKWRKR-------ERNQ--------QAELCKNSFGAQFNGLMQP 141

  Fly   294 SDDIPDSTSNSRGHNN-------NTPSATNNNP--SAGNLTPNSSLETGISSNLMGSTTVSASNV 349
            .||:....|    :||       .:|.:..:.|  ::.|::|.||.......|.:.|.|:.:|.|
 Frog   142 YDDMYSGYS----YNNWATKGLATSPLSAKSFPFFNSMNVSPLSSQPMFSPPNSIASMTMPSSMV 202

  Fly   350 ISADSSVASSVSLDE--DIEE-SSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENS-TPSLVSFR 410
            .||.:.|..| ||:.  :|.. :||      .....:...|...:|.|||:.|.:: ..||.|.|
 Frog   203 PSAVTGVPGS-SLNNLGNINNLNSP------SLNSAVSASACPYASTASPYMYRDTCNSSLASLR 260

  Fly   411  410
             Frog   261  260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
pitx3	XP_002935807.2	Homeodomain	61..117	CDD:459649	28/55 (51%)
		OAR	250..267	CDD:461067	4/11 (36%)