DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and pdx1

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	XP_002934065.1	Gene:	pdx1 / 100490648	XenbaseID:	XB-GENE-483331	Length:	271	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	73/208 - (35%)
Similarity:	105/208 - (50%)	Gaps:	45/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 GVGYPVGVVPQTPDGMDSVP---------EYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPR 199
            |:.:|...:| .||..:|..         .:||||..|      ::..:|..:...::.|....:
Frog    91 GIPHPHQQMP-FPDDTESATLEERNRTLLPFPWMKSTK------SHTWKGQWTGGSYIMEQEENK 148

  Fly   200 RLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDE 264
            |.|||||..|||||||||.||||:.||||:|:|..|:||||.:|:||||||||.|:        |
Frog   149 RTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKK--------E 205

  Fly   265 DNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSS 329
            ::|...:|.|.:.||..:|          :|.|.|.           |....|:.:.|:|..:|:
Frog   206 EDKKRGRGSDPEQDSVVSS----------ADVIKDE-----------PQCLGNSQNTGDLVRSSA 249

  Fly   330 LETGISSNLMGST 342
            |.|...||.:.:|
Frog   250 LPTSPQSNPIPAT 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	48/105 (46%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	38/51 (75%)
pdx1	XP_002934065.1	Homeobox	150..204	CDD:365835	38/53 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910