Protein Alignment pb and hoxa3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001120901.1
• Gene: hoxa3 / 100151729
• XenbaseID: XB-GENE-482267
• Length: 406
• Species: Xenopus tropicalis
• Alignment Length: 702
• Identity: 146/702 - (20%)
• Similarity: 198/702 - (28%)
• Gaps: 325/702 - (46%)

  Fly    43 AGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAY------WMTASEGGFI 101
            :.:.||....|.:.......||..||..|:|......|.|..:|..:|.      .:..|....|
 Frog    10 SAIYGGYPYQGANGFTYNASQQQYPPSSSLLETEYHRPACSLQSPGSAVPHHKANDINESCMRTI 74

  Fly   102 NSQPSMAEFLNHLSP----ESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSV 162
            |||.:.|..:....|    ..|.:..|..:........|...::             |...| |.
 Frog    75 NSQSNQAPVIPEQQPTPQGPPPSVSPPQTTSNAATASSNKATSI-------------TSPTM-SK 125

  Fly   163 PEYPWMKEKKTSRK-------SSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFN 220
            ..:|||||.:.:.|       ||..:..||.|    .|.....:|.|||||:.||:|||||||||
 Frog   126 QIFPWMKESRQNTKQQKAGSSSSGESCAGDKS----PPGQSSSKRARTAYTSAQLVELEKEFHFN 186

  Fly   221 KYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKK 285
            :|||||||:|:|..|:|||||:|:||||||||:|:       |:..|..:.....||.
 Frog   187 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK-------DQKGKSMMTSSGGQSP------- 237

  Fly   286 SCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVI 350
                |..|   :|                   .||.|
 Frog   238 ----CRSP---VP-------------------TPSVG---------------------------- 248

  Fly   351 SADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENSTPSLVSFRRDSDA 415
                                                           ||.||..|||
 Frog   249 -----------------------------------------------GYLNSMHSLV-------- 258

  Fly   416 SAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQ 480
            ::|...|.|.....|...|   |...|.|                      ||||       ...
 Frog   259 NSVPYEPQSPPAFNKHHPS---AYGVPAP----------------------YPSP-------HNS 291

  Fly   481 LHPQQQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQNDH 545
            ..|.|:            :|....|.:|.:.||..||: .|.|
 Frog   292 CPPHQK------------RYSGTAAVTPEYEPHPLQQS-SGAY---------------------- 321

  Fly   546 FYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGPVNGPSNFNNGAYYDNMSFQQQA 610
                     |.|:                              |.|...:..|.|.:.|:
 Frog   322 ---------GNPH------------------------------VQGSPVYVGGNYVETMT----- 342

  Fly   611 QAHQHQTVVFQQQQPHQPAAINHQHMHHLGNGETYSALGLQMENCEGYNNFGAAGTGGGYYEAGQ 675
                          ...|:.....|:.|..:...||..|
 Frog   343 --------------NSGPSMFGLSHLSHSSSNMDYSGAG-------------------------- 367

  Fly   676 QPPIPATHGHG---HHPHHVQVPAQAHAPIHAHHNSAAIPGGVGVGPPPSHI 724
              |:.:.|.||   .||        .:..:.||||.   .|.:...|..:|:
 Frog   368 --PMNSGHHHGPCDSHP--------TYTDLSAHHNP---QGRIQEAPKLTHL 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	41/55 (75%)
hoxa3	NP_001120901.1	Homeodomain	165..221	CDD:459649	41/55 (75%)
		DUF4074	343..404	CDD:463833	18/99 (18%)