DRSC/TRiP Functional Genomics Resources

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Protein Alignment Edg84A and Cntrl

DIOPT Version :9

Sequence 1:NP_524247.1 Gene:Edg84A / 40818 FlyBaseID:FBgn0000552 Length:188 Species:Drosophila melanogaster
Sequence 2:NP_001366203.1 Gene:Cntrl / 26920 MGIID:1889576 Length:2334 Species:Mus musculus


Alignment Length:193 Identity:42/193 - (21%)
Similarity:69/193 - (35%) Gaps:53/193 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 PLPA---KSSGSEDTYDS--HPQYSFNYDVQDPETGDVKSQSESRDG----------------DV 62
            |.|:   .|..|:.|.||  ..:|:.:..::.|:.|    |.|.:|.                ..
Mouse  1150 PAPSSKVSSHSSQATKDSGLGLKYTASTPLRKPQPG----QQEEKDSSGPLPASGYWVYSPIRST 1210

  Fly    63 VHGQYSV-NDADGYRRTVDYTADDVRGFNAVVRRE------PLSSAAVVVKPQATAVVPKVQL-K 119
            :|..:|. .|||        :..|.:..:.:..:|      |.......|.|..:.|...|.| .
Mouse  1211 LHKSFSKREDAD--------SGGDSQEESGLDDQEEPPFVPPPGYIMYTVLPDGSPVPQGVALYA 1267

  Fly   120 PLKKLP-ALKPLSQASAVVHRSFAPVVHHAPVTHVVHHAAPAHSFVSHHVPVLKTTVHHAHHP 181
            |...|| :..||:..:.|    :.|....||:.    :..|..:|.   ||::...|.|.:.|
Mouse  1268 PSPPLPNSSHPLTPGTVV----YGPPPAGAPII----YGPPPANFA---VPLVPAGVQHCNIP 1319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Edg84ANP_524247.1 Chitin_bind_4 37..89 CDD:278791 12/68 (18%)
CntrlNP_001366203.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..70
PPP1R42 89..261 CDD:411060
leucine-rich repeat 100..119 CDD:275378
LRR 1 126..147
leucine-rich repeat 127..148 CDD:275380
LRR 2 148..169
leucine-rich repeat 149..170 CDD:275380
LRR 3 170..191
leucine-rich repeat 171..194 CDD:275380
LRR 4 194..215
leucine-rich repeat 195..219 CDD:275380
leucine-rich repeat 220..246 CDD:275380
Smc <270..602 CDD:224117
Smc 440..>1134 CDD:224117
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..562
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 751..771
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1154..1198 11/47 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1213..1245 6/39 (15%)
Drf_FH1 <1239..1310 CDD:399386 19/81 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1338..1360
SMC_prok_B 1407..2216 CDD:274008
Required for centrosome localization. /evidence=ECO:0000250 1951..2121
Sufficient for interaction with HOOK2. /evidence=ECO:0000250 1988..2334
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2291..2334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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