Protein Alignment lab and Cdx2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_076453.1
• Gene: Cdx2 / 66019
• RGDID: 621234
• Length: 310
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 89/334 - (26%)
• Similarity: 126/334 - (37%)
• Gaps: 100/334 - (29%)

  Fly   338 HQNSVSPNGGMNRQQRGGVISP------GSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQ 396
            :.:||..:||:|...:..|..|      |...:::.:|:  |:..|.||..|    |.||
  Rat    14 YPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAA--ANLDSAQSPGP----SWPT----- 67

  Fly   397 LKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNG-----PVGVGGNGSPG--- 453
                          |.|.....|:  ||   ...||....:.|.:|     |....|..||.
  Rat    68 --------------AYGAPLREDW--NG---YAPGGAAAANAVAHGLNGGSPAAAMGYSSPAEYH 113

  Fly   454 ------------------IGGVLSVQNSLIMANSA-AAAGSAHPNGM------------GVGLGS 487
                              ..|:|...|......:| |||....|:|.            ...|||
  Rat   114 AHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPSGQRRNLCEWMRKPAQPSLGS 178

  Fly   488 GSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNR 552
                   .:.:.|.:..|..:|:.|..|||||||::||:|..|:.|:|.||.|:|.|||||||||
  Rat   179 -------QVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNR 236

  Fly   553 RMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTT 617
            |.|::|                  :..:|..||||.|||............|...:...|.:|.|
  Rat   237 RAKERK------------------INKKKLQQQQQQQPPAPPPPQPSQPQSGALRSVPEPLSPVT 283

  Fly   618 AMTLTAPTS 626
            ::..:.|.|
  Rat   284 SLQGSVPGS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	31/52 (60%)
Cdx2	NP_076453.1	Caudal_act	13..178	CDD:461413	40/193 (21%)
		Homeodomain	187..242	CDD:459649	31/54 (57%)