Protein Alignment lab and hoxb5b

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_571612.2
• Gene: hoxb5b / 58052
• ZFINID: ZDB-GENE-000823-6
• Length: 276
• Species: Danio rerio
• Alignment Length: 321
• Identity: 78/321 - (24%)
• Similarity: 107/321 - (33%)
• Gaps: 141/321 - (43%)

  Fly   281 DSLGMHA----HMHHGLP-------HGHLGNLANNPHQ-QQPQVQQQQQQPHQQPQHP------- 326
            ||..||:    :.::|:.       :||.|.:.:|... |.|..:.:.:|.......|
Zfish    36 DSTSMHSGSFGYNYNGIDLSVNRPNNGHFGAVGDNSRAFQNPSQETRYRQSSCSLSSPDPLSCAT 100

  Fly   327 ------QNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSS-------TSSSTSASNGA----- 373
                  :..||.:.|.      :|.|.........:.|..|:       |:.|:....||
Zfish   101 SDTLELKGSSPPSDQS------TPTGNSRLTNSNNLTSSNSTHFADTDETNVSSETEEGAQTTTT 159

  Fly   374 ------HPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGG 432
                  ...:|.:.:||...:...:.||:           ||..|     ||  |.|
Zfish   160 SRTQKQESVATSTTTPNDGQTPQIFPWMR-----------KLHIS-----HD--MTG-------- 198

  Fly   433 GGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLS 497
                                                         |:|
Zfish   199 ---------------------------------------------PDG----------------- 201

  Fly   498 SNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKK 558
                ...||.:|..|..||||||||||||||.||||||:.|.|:|.|:||||||||||.||
Zfish   202 ----KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	38/52 (73%)
hoxb5b	NP_571612.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..182		21/124 (17%)
		Antp-type hexapeptide	183..188		1/4 (25%)
		Homeodomain	202..258	CDD:459649	38/55 (69%)