Protein Alignment lab and nkx6.3

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001159612.1
• Gene: nkx6.3 / 558978
• ZFINID: ZDB-GENE-070810-7
• Length: 272
• Species: Danio rerio
• Alignment Length: 260
• Identity: 65/260 - (25%)
• Similarity: 98/260 - (37%)
• Gaps: 50/260 - (19%)

  Fly   361 SSTSSSTSASNGAHPASTQSKSPNHSSSIPT--YKW------MQLKRNVPKPQAPKLPASGIASM 417
            |:.|.|...:|..:...:..|:|....|||.  ||.      .||:...|         .||:.:
Zfish     3 SNISGSFLFNNSLNQFPSDIKAPVCQYSIPNSFYKLGPANINSQLQAGTP---------HGISDI 58

  Fly   418 HDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNG----SPGI--------GGVLSVQNSLIMANSA 470
                    |......|.|...:.:|...:||.|    |||:        .|:.:....::  ..|
Zfish    59 --------LSRSMVSGPGTPALLSGYPSMGGFGTTVPSPGVYYNRDYTPSGLSTFPKPVV--ECA 113

  Fly   471 AAAGSAHPNGMGVGLGSGSGLSSC--SLSSNTNNSG-----RTNFTNKQLTELEKEFHFNRYLTR 528
            ...|.:....:..|.........|  ::..|..|.|     |..|:..|:..|||.|...:||..
Zfish   114 GMKGKSSSCWVDGGYEWRGARQQCGNNMGHNPENVGKKKHTRPTFSGHQIFALEKTFEQTKYLAG 178

  Fly   529 ARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSV--ISEKPPQQQQPQPP 591
            ..|..:|.:|.:.|:|||:||||||.|.:|  |....|:...|....|.  .||...:.::...|
Zfish   179 PERARLAYSLGMTESQVKVWFQNRRTKWRK--KSATEPSSTQTSRGESAGDGSENEVEDEEYNKP 241

  Fly   592  591
            Zfish   242  241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	23/52 (44%)
nkx6.3	NP_001159612.1	Homeodomain	150..208	CDD:459649	23/57 (40%)