DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lab and hoxb4

DIOPT Version :9

Sequence 1:NP_476613.1 Gene:lab / 40817 FlyBaseID:FBgn0002522 Length:629 Species:Drosophila melanogaster
Sequence 2:NP_001116487.1 Gene:hoxb4 / 548393 XenbaseID:XB-GENE-1033882 Length:234 Species:Xenopus tropicalis


Alignment Length:328 Identity:79/328 - (24%)
Similarity:119/328 - (36%) Gaps:121/328 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 WHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQ-QPQVQQQQQQPHQQPQHPQN 328
            :.|..:|...::.:........:...||.|:....:.::.|:.. |..|:|..:.||.....|  
 Frog    23 YSHTDYLPSGHSPEYYGGQKRESSFQHGAPYSRSLSSSSAPYTSCQGSVRQGARLPHSSGLLP-- 85

  Fly   329 QSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYK 393
                ..:.|.::|::|.               |..|.|..||:..||     .||.....:  |.
 Frog    86 ----GEKAHLESSITPT---------------SPPSCSLIASDHKHP-----DSPGQDPVV--YP 124

  Fly   394 WMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVL 458
            ||: |.::.:                                                       
 Frog   125 WMK-KAHISR------------------------------------------------------- 133

  Fly   459 SVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFN 523
                    |:|..:.|.|                         ...||.:|.:|:.|||||||:|
 Frog   134 --------ASSTYSDGEA-------------------------KRSRTAYTRQQVLELEKEFHYN 165

  Fly   524 RYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSV-ISEKPPQQQQ 587
            |||||.||:|||:||:|:|.|:||||||||||.||..|  |....|.:..|.:: |:...|.|.:
 Frog   166 RYLTRRRRVEIAHTLRLSERQIKIWFQNRRMKWKKDHK--LPNTKIRSNPSVNLQIAGGSPNQNK 228

  Fly   588 PQP 590
            ..|
 Frog   229 GNP 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
labNP_476613.1 Homeobox 505..557 CDD:278475 37/51 (73%)
hoxb4NP_001116487.1 Homeobox 146..200 CDD:365835 37/53 (70%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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