Protein Alignment lab and hoxb4

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001116487.1
• Gene: hoxb4 / 548393
• XenbaseID: XB-GENE-1033882
• Length: 234
• Species: Xenopus tropicalis
• Alignment Length: 328
• Identity: 79/328 - (24%)
• Similarity: 119/328 - (36%)
• Gaps: 121/328 - (36%)

  Fly   265 WHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQ-QPQVQQQQQQPHQQPQHPQN 328
            :.|..:|...::.:........:...||.|:....:.::.|:.. |..|:|..:.||.....|
 Frog    23 YSHTDYLPSGHSPEYYGGQKRESSFQHGAPYSRSLSSSSAPYTSCQGSVRQGARLPHSSGLLP-- 85

  Fly   329 QSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYK 393
                ..:.|.::|::|.               |..|.|..||:..||     .||.....:  |.
 Frog    86 ----GEKAHLESSITPT---------------SPPSCSLIASDHKHP-----DSPGQDPVV--YP 124

  Fly   394 WMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVL 458
            ||: |.::.:
 Frog   125 WMK-KAHISR------------------------------------------------------- 133

  Fly   459 SVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFN 523
                    |:|..:.|.|                         ...||.:|.:|:.|||||||:|
 Frog   134 --------ASSTYSDGEA-------------------------KRSRTAYTRQQVLELEKEFHYN 165

  Fly   524 RYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSV-ISEKPPQQQQ 587
            |||||.||:|||:||:|:|.|:||||||||||.||..|  |....|.:..|.:: |:...|.|.:
 Frog   166 RYLTRRRRVEIAHTLRLSERQIKIWFQNRRMKWKKDHK--LPNTKIRSNPSVNLQIAGGSPNQNK 228

  Fly   588 PQP 590
            ..|
 Frog   229 GNP 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxb4	NP_001116487.1	Homeodomain	144..200	CDD:459649	37/55 (67%)