DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lab and Hoxa7

DIOPT Version :9

Sequence 1:	NP_476613.1	Gene:	lab / 40817	FlyBaseID:	FBgn0002522	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001102703.2	Gene:	Hoxa7 / 500126	RGDID:	1587253	Length:	229	Species:	Rattus norvegicus

Alignment Length:	198	Identity:	66/198 - (33%)
Similarity:	86/198 - (43%)	Gaps:	54/198 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   437 SGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGV---------------GLG 486
            ||.|.| .|...:..||:..|    ||.:..|..|::     .|:|.               ||.
  Rat    38 SGYGPG-AGAFASNVPGLYNV----NSPLYQNPFASS-----YGLGADAYNLPCASYDQNIPGLC 92

  Fly   487 SGSGLSSCS----------------------LSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRA 529
            |.....:|.                      .|......||..:|..|..||||||||||||||.
  Rat    93 SDLAKGACDKADEGVLHGPAEASFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRR 157

  Fly   530 RRIEIANTLQLNETQVKIWFQNRRMKQKKRVKE-----GLIPADILTQHSTSVISEKPPQQQQPQ 589
            ||||||:.|.|.|.|:||||||||||.||..|:     ..:|.|.:.  |.|..::|..::::.:
  Rat   158 RRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDESQAPTAVPEDAVP--SVSTAADKADEEEEEE 220

  Fly   590 PPE 592
            ..|
  Rat   221 EEE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	37/51 (73%)
Hoxa7	NP_001102703.2	Homeobox	133..185	CDD:278475	37/51 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900