Protein Alignment lab and Lbx1

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001040573.1
• Gene: Lbx1 / 499362
• RGDID: 1564197
• Length: 285
• Species: Rattus norvegicus
• Alignment Length: 295
• Identity: 76/295 - (25%)
• Similarity: 104/295 - (35%)
• Gaps: 71/295 - (24%)

  Fly   367 TSASNG-AHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHD----------Y 420
            ||..:| |.|...:.:||......|.        |..||..|       .|:.|          |
  Rat     2 TSKEDGKAAPGEERRRSPLDHLPPPA--------NSNKPLTP-------FSIEDILNKPSVRRSY 51

  Fly   421 QMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVG- 484
            .:.|...:.........|           |.|..|..|..|.|.:.|....|:.:.  .|:.|.
  Rat    52 SLCGAAHLLAAADKHAPG-----------GLPLAGRALLSQTSPLCALEELASKTF--KGLEVSV 103

  Fly   485 LGSGSGLSSCSL-----SSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQ 544
            |.:..|....::     :.......||.|||.|:.||||.|.:.:||:.|.|.:||..|.|...|
  Rat   104 LQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQ 168

  Fly   545 VKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQP--QPPELQLKSQGSDLGGN-- 605
            |..||||||.|.|:.::|  :.||:.:.....      |..|..  ...||:..|:.|..||.
  Rat   169 VITWFQNRRAKLKRDLEE--MKADVESAKKLG------PSGQMDIVALAELEQNSEASGGGGGGG 225

  Fly   606 --------------ELATGAPSTPTTAMTLTAPTS 626
                          .|..|||..|.......:|.|
  Rat   226 GGGCGRAKSRPGSPALPPGAPQAPGGGPLQLSPAS 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	28/52 (54%)
Lbx1	NP_001040573.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		12/48 (25%)
		Homeodomain	126..182	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..285		11/49 (22%)