Protein Alignment lab and Hoxb4

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001094257.1
• Gene: Hoxb4 / 497988
• RGDID: 1560113
• Length: 250
• Species: Rattus norvegicus
• Alignment Length: 368
• Identity: 90/368 - (24%)
• Similarity: 125/368 - (33%)
• Gaps: 136/368 - (36%)

  Fly   238 VLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLA 302
            :::::|     ::.:.|..::.:||. :....|..|.||.......|..       |....|..|
  Rat     7 LINSNY-----VDPKFPPCEEYSQSD-YLPSDHSPGYYAGGQRRESGFQ-------PEAAFGRRA 58

  Fly   303 ----------NNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVI 357
                      .:|....|       .|...|..|...||.|..|....::.|..|    ||..|:
  Rat    59 PCTVQRYAACRDPGPPPP-------PPPPPPPPPPGLSPRAPVQSTAGALLPEPG----QRSEVV 112

  Fly   358 SPGSSTSSSTSASNGAHPASTQSKSPNHSS--SIPTYKWMQLKRNVPKPQAPKLPASGIASMHDY 420
            |  ||......|.|..||      ||:||:  ....|.||:                   .:|
  Rat   113 S--SSPPPPPCAQNPLHP------SPSHSACKEPVVYPWMR-------------------KVH-- 148

  Fly   421 QMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGL 485
                                                                ..:.:||..|
  Rat   149 ----------------------------------------------------VSTVNPNYAG--- 158

  Fly   486 GSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQ 550
                         ......||.:|.:|:.|||||||:||||||.||:|||:.|.|:|.|:|||||
  Rat   159 -------------GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQ 210

  Fly   551 NRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPEL 593
            |||||.||..|   :|...:....|:..:..||.:....||.|
  Rat   211 NRRMKWKKDHK---LPNTKIRSGGTAGAAGGPPGRPNGGPPAL 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	36/52 (69%)
Hoxb4	NP_001094257.1	Homeodomain	162..218	CDD:459649	36/55 (65%)