DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lab and Hoxb6

DIOPT Version :9

Sequence 1:	NP_476613.1	Gene:	lab / 40817	FlyBaseID:	FBgn0002522	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_006247294.1	Gene:	Hoxb6 / 497986	RGDID:	1562142	Length:	224	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	77/247 - (31%)
Similarity:	97/247 - (39%)	Gaps:	62/247 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 NGAHPASTQSKSPNHSSSIPTYK--WMQLKRNVPKPQAPKLPA--SGIASMHDYQMNGQLDMCRG 431
            |...|.:..|...:....:|.|.  :....|:.|.|..|. |.  .|.|:...|...|      |
  Rat     7 NSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPG-PGQDKGFAASSYYPPAG------G 64

  Fly   432 GGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSA-------HPNGMGVGLGSGS 489
            |.|..:....||       :|          :......||.|.|.       ||...........
  Rat    65 GYGRAAPCDYGP-------AP----------AFYREKDAACALSGADEPPPFHPEPRKSDCAQDK 112

  Fly   490 G--------------------LSSCSLSS--NTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRI 532
            .                    ::||:.||  .:...||..:|..|..|||||||:||||||.|||
  Rat   113 SVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRI 177

  Fly   533 EIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQ 584
            |||:.|.|.|.|:||||||||||.||..|  |:.|   :|.|.....|||.:
  Rat   178 EIAHALCLTERQIKIWFQNRRMKWKKESK--LLSA---SQLSAEEEEEKPAE 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	36/51 (71%)
Hoxb6	XP_006247294.1	Homeobox	150..203	CDD:395001	36/52 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900