Protein Alignment lab and gbx2.2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001011472.1
• Gene: gbx2.2 / 496963
• XenbaseID: XB-GENE-852624
• Length: 340
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 83/305 - (27%)
• Similarity: 118/305 - (38%)
• Gaps: 108/305 - (35%)

  Fly   305 PHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSA 369
            |....|.:.|...||.....||          |||....|:...:...:|..:     ||:..::
 Frog    58 PPPPPPSLSQATLQPTLPSAHP----------HHQIPSLPSAFCSSLAQGMAL-----TSTLMAS 107

  Fly   370 SNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGG 434
            ..|...||.|     |..::..:                    |..|:|     |..:..:||..
 Frog   108 LPGGFSASAQ-----HQKAVRKF--------------------GAQSLH-----GAFEKSKGGQS 142

  Fly   435 -------------------GGSGVGNGPV-GVG----GNGSPGIGGVLSVQNSLIM-------AN 468
                               ..|....||| |.|    |..:.|.|    .::|.:|       ::
 Frog   143 DEEDGNKTYITKEGTLLPFSASEASLGPVRGQGKEESGKEAEGKG----KEDSYLMDSDLDYSSD 203

  Fly   469 SAAAAGSAH----------PNGMGVGLGSGSGLSSCSLSSNTNNSG-----RTNFTNKQLTELEK 518
            ...:..:||          ||            |:.|.:|||:::|     ||.||::||.||||
 Frog   204 DNISCQTAHKEDDTPEESPPN------------SNPSNNSNTSSTGKNRRRRTAFTSEQLLELEK 256

  Fly   519 EFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEG 563
            |||..:||:...|.:||:.|:|:|.||||||||||.|. ||||.|
 Frog   257 EFHCKKYLSLTERSQIAHVLKLSEVQVKIWFQNRRAKW-KRVKAG 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	32/52 (62%)
gbx2.2	NP_001011472.1	Homeodomain	240..296	CDD:459649	32/56 (57%)