Protein Alignment lab and E5

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 103/500 - (20%)
• Similarity: 148/500 - (29%)
• Gaps: 200/500 - (40%)

  Fly   114 PHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYAT------AAVATVAP 172
            |.|...|.|::   :..|:|:.:..:.:..|:.|.....:..||:....:|      .:|.:..|
  Fly    16 PTSPFVSSSSS---VAASSTSVSASSTVSASASSKPKLAFSIDSIVGESSTRSAPLRVSVISSPP 77

  Fly   173 PSNSSPITAANASATSNTQQQQQQAAIISSENGMMY----TNLD-----CMYPTAQAQAPVHGYA 228
            |.:.||.:..|   |:|:.::        :..|.:|    .:||     ...|.:::.:|.:...
  Fly    78 PRSESPASPTN---TNNSGRR--------TPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGG 131

  Fly   229 GQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYAL-------DAMDSLGMH 286
            ...            |.|...:..||.........:.......|.:.||       :||
  Fly   132 NPA------------AAGNTAKSGDPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNAM------ 178

  Fly   287 AHMHHGLPH----------GHLGNLANNPHQQQPQVQQQQQQ--------PH-QQPQHPQNQSPA 332
            |....|.||          ......|...|..|.|.||||||        || ..|..|..|.|.
  Fly   179 AVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPL 243

  Fly   333 AHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNH--SSSIPTYKWM 395
                    .:.|.|.          .||.      ...:|.||..    |..|  ..|.|.|.|:
  Fly   244 --------GIFPGGP----------HPGH------PPPHGHHPFG----SAPHLIRDSYPLYPWL 280

  Fly   396 QLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGN-------GPVGVGGNGSPG 453
            ..:.....|:.|                                ||       .|..|
  Fly   281 LSRHGRIFPRFP--------------------------------GNFLFQPFRKPKRV------- 306

  Fly   454 IGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEK 518
                                                               ||.|:..||.:||.
  Fly   307 ---------------------------------------------------RTAFSPTQLLKLEH 320

  Fly   519 EFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEG 563
            .|..|.|:..|.|.::|..|.|.|||||:||||||.|.|:..:||
  Fly   321 AFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEG 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	27/52 (52%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	28/113 (25%)