Protein Alignment lab and Dr

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 139/606 - (22%)
• Similarity: 211/606 - (34%)
• Gaps: 203/606 - (33%)

  Fly    17 PHANAYDGYSTTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYP 81
            |.:|...|....|:|::|:.|                               |...:.|.||...
  Fly    25 PSSNTPAGNLIITSSSSNSGS-------------------------------NSGSNMSSGNMTS 58

  Fly    82 QQQAQLTP----------PPTS------SHQ--VVQQHQQQQQAQQQQ----------LYP---H 115
            .....|:|          .|||      :||  ::|||||.||.||||          ::|   |
  Fly    59 SNLTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHH 123

  Fly   116 SHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPIT 180
            .|..:...:.:.:.:......|.||.:.::..|          .:..::||.:.::..|::.|..
  Fly   124 LHKTTSRLSNFSVASLLADTRPRTPPNQAADGP----------QNLTSSAATSPISQASSTPPPP 178

  Fly   181 AANASA--TSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASY 243
            .|:|:|  .:||                       .:|.|.|.             :|.:|.|::
  Fly   179 PASAAAQVPANT-----------------------FHPAAVAH-------------HAHLLQAAH 207

  Fly   244 APGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQ 308
            |..........|..|..|.|    ||..|.:.:..|..| ...:....|...|..||:|:.|.:.
  Fly   208 AAAAAHAQHQAMAAQLRQQQ----QQADARANSPPASTS-STPSSTPLGSALGSQGNVASTPAKN 267

  Fly   309 QP------------QVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMN-----RQQRGGV 356
            :.            :..::..|.|:           |.....::|:.....||     |....|:
  Fly   268 ERHSPLGSHTDSELEYDEEMLQDHE-----------ADHDEEEDSIVDIEDMNADDSPRSTPDGL 321

  Fly   357 ISPGSSTSSSTSASNGAHPAST-QSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDY 420
            ...|.|..|......|:|..|| .|.:...|..:|..         |.|.: .|.|:.:|
  Fly   322 DGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIR---------PTPFS-ALAAAAVA----- 371

  Fly   421 QMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGL 485
                           .:|:|.|....|....|..|                      |.||..|.
  Fly   372 ---------------WTGMGGGVPWPGTRQMPPFG----------------------PPGMFPGA 399

  Fly   486 GSGSGLS-----SCSLSSN-TNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQ 544
            |.|...:     .|:|..: .|...||.||.:||..|||:|...:||:.|.|.|.:::|:|.|||
  Fly   400 GFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQ 464

  Fly   545 VKIWFQNRRMKQKKRVKEGLI 565
            |||||||||.| .||::|..|
  Fly   465 VKIWFQNRRAK-AKRLQEAEI 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	30/52 (58%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	30/56 (54%)