Protein Alignment lab and cdx2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_989209.1
• Gene: cdx2 / 394817
• XenbaseID: XB-GENE-483306
• Length: 252
• Species: Xenopus tropicalis
• Alignment Length: 309
• Identity: 86/309 - (27%)
• Similarity: 115/309 - (37%)
• Gaps: 83/309 - (26%)

  Fly   319 PHQQPQHPQNQS-PAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASN-----GAHPAS 377
            |.....||..|: |||.|.....|..   ||....  |..|.|||....|....     |.||
 Frog    15 PGSMRAHPGLQNYPAAPQYPDYGSYH---GMGLDH--GAPSSGSSAGWITPYGPPRDEWGVHP-- 72

  Fly   378 TQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDY---QMNGQLDMCRGGGGGGSGV 439
              :.||.|:...|:                  |...:|...||   |:.||  .|         |
 Frog    73 --TYSPGHTHINPS------------------PVGNMAFSPDYSPAQVQGQ--PC---------V 106

  Fly   440 GNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSG 504
            |..|.|.....|||                   :...|.......|......:|....:.|.:..
 Frog   107 GVLPAGPPPQLSPG-------------------SEDGHRRHHYEWLRKPVSQASTGSKTRTKDKY 152

  Fly   505 RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADI 569
            |..:|::|..|||||||::||:|..|:.|:|..|.|:|.||||||||||.|::|..|:.
 Frog   153 RVVYTDQQRLELEKEFHYSRYITIRRKAELAANLGLSERQVKIWFQNRRAKERKITKKR------ 211

  Fly   570 LTQHSTSVISEKPPQQQQPQP--PELQLKSQGSDLGGNELATGAPSTPT 616
            :.|..|   .:..|....|:|  ....:....|::|      |.|:|.|
 Frog   212 IQQTQT---GQNGPDTLSPEPSITHHMIPHATSNVG------GLPNTVT 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	30/52 (58%)
cdx2	NP_989209.1	Caudal_act	13..143	CDD:461413	42/184 (23%)
		Homeodomain	151..206	CDD:459649	30/54 (56%)