Protein Alignment lab and Lmx1a

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 77/300 - (25%)
• Similarity: 104/300 - (34%)
• Gaps: 96/300 - (32%)

  Fly   268 QQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANN-------------------PHQ--QQPQ 311
            ||:..|:..||..:...|.|...:.|   ||.|..||                   .||  ||.|
  Fly    22 QQNHGGARFLDNPNPGSMTASSGNSL---HLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQ 83

  Fly   312 VQQQQQQPHQQPQHPQNQ--------------SPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSS 362
            .|||||.||||.|..|.|              :|..|.....:|.:.|...|.....|    |||
  Fly    84 HQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNG----GSS 144

  Fly   363 TSSSTSASN--------GAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHD 419
            :::..||.|        .|..|:..:.||..:|             |...|.....|:.||:...
  Fly   145 SNNLHSACNTLTAAAVAAASAAAVAAPSPAGTS-------------VATSQLGGAVAAAIAAAAA 196

  Fly   420 YQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVG 484
            ...........|....|||..||    .|||:                      |:.:.||.|.|
  Fly   197 AAAAATTPTSTGPAATGSGNANG----SGNGN----------------------GNGNGNGNGNG 235

  Fly   485 LGSGSGLSSCSLSS----NTNNSGRTNFTNKQLTELEKEF 520
            .|:|.|.::.|.::    :.:.||||...:   .:.||.|
  Fly   236 NGNGGGAATASAAAASKLSADCSGRTEVGH---IKCEKNF 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	4/15 (27%)
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757
		LIM	333..388	CDD:413332
		Homeodomain	425..481	CDD:459649