Protein Alignment lab and Dll

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 71/289 - (24%)
• Similarity: 107/289 - (37%)
• Gaps: 82/289 - (28%)

  Fly   404 PQAPKLP---------ASGIASMHDYQMNGQLDMCRGGGGGGSGVGN-----GPVGVGGNGSPGI 454
            |.||..|         ||....::....:..:::.:....|..|:.:     ||.|...:|.|..
  Fly     4 PDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSP 68

  Fly   455 GGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSC--------SLSSNTNNSG------- 504
            ...|......:..||.:            |...||....|        |:|....:||
  Fly    69 RSALGYPFPPMHQNSYS------------GYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGKG 121

  Fly   505 ------RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEG 563
                  ||.:::.||.:|.:.|...:||....|.|:|.:|.|.:|||||||||||.|.||.:|..
  Fly   122 KKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAA 186

  Fly   564 LIPADILTQHSTSVISEKPPQQQQPQPPELQ-------------LKSQGS-----DLGGNE---L 607
            ..|.    .:|...:....|...|..|.::.             |::.|:     ..|||.   .
  Fly   187 QGPG----TNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGS 247

  Fly   608 ATGAPS-------TPTTAMTLTAPTSKQS 629
            .:|:||       :||.:.|   |.|:.|
  Fly   248 NSGSPSHYLPPGHSPTPSST---PVSELS 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	25/52 (48%)
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	25/55 (45%)