DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lab and Meox1

DIOPT Version :9

Sequence 1:	NP_476613.1	Gene:	lab / 40817	FlyBaseID:	FBgn0002522	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001102307.1	Gene:	Meox1 / 363684	RGDID:	1308911	Length:	253	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	77/251 - (30%)
Similarity:	105/251 - (41%)	Gaps:	60/251 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 SSSTSASNGAH----PASTQSKS--------PNHSS--------SIPTYKWMQLKRNVPKPQAP- 407
            |..:|||...|    |.|...||        |:.|:        |:|..:.:..:::...||.|
  Rat    27 SEGSSASGLPHYPPTPFSFHQKSDFPATAAYPDFSTSCLAATPHSLPRAERIFNEQHPAFPQTPD 91

  Fly   408 -KLPASGIASMHDYQMN-GQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSA 470
             ..|.|....    ::| |.....|..|.|..|:.:|..|:|.:..  :.|.::.:....::...
  Rat    92 WHFPISEAGQ----RLNLGPAGSAREMGAGSPGLVDGTGGLGEDCM--VLGTIAHETEKKLSRRK 150

  Fly   471 AAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIA 535
            ........||.|...||...           ...||.||.:||.|||.||..:.||||.||.|||
  Rat   151 KERSDNPENGGGKPEGSSKA-----------RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIA 204

  Fly   536 NTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKP--PQQQQPQ 589
            ..|.|:|.|||:||||||||. ||||.|                 :|  ||:|.|:
  Rat   205 VNLDLSERQVKVWFQNRRMKW-KRVKGG-----------------QPVSPQEQDPE 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	34/51 (67%)
Meox1	NP_001102307.1	COG5576	139..251	CDD:227863	49/133 (37%)
Meox1	NP_001102307.1	Homeobox	174..227	CDD:395001	34/53 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810