Protein Alignment lab and Gsc

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001137762.2
• Gene: Gsc / 33240
• FlyBaseID: FBgn0010323
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 125/575 - (21%)
• Similarity: 190/575 - (33%)
• Gaps: 197/575 - (34%)

  Fly   116 SHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPPSNSSPIT 180
            |.|::|.....|.||:|.:..|..|  ||.                 |...:..|:.||.|.|.|
  Fly     3 SSLWTPGGGGGGTTTTTPSTTPDIP--PSK-----------------AKFKITVVSTPSPSPPPT 48

  Fly   181 AANAS--------------------ATSNTQQQQQQAAIISSENG----------MMYTNLDCMY 215
            ...|.                    :.|:..:|||....||...|          |:..:..|
  Fly    49 PPPAGSMLAQMVETNSPPAGYTLKRSPSDLGEQQQPPRQISRSPGNTAAYHLTTAMLLNSQQC-- 111

  Fly   216 PTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYA---L 277
                      ||.||   :..:||...:|.....:.|.|.....:||.:...::...|..|   |
  Fly   112 ----------GYLGQ---RLQSVLQQQHAQHQQSQSQTPSSDDGSQSGVTILEEERRGGAAAASL 163

  Fly   278 DAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHHQNSV 342
            ..:||:              ||:              :||.....|    :|........:||.:
  Fly   164 FTIDSI--------------LGS--------------RQQGGGTAP----SQGSHISSNGNQNGL 196

  Fly   343 SPNG---GMNRQQRGGVISPGSSTSSSTSAS-------------NGAH-------PASTQSKSPN 384
            :.||   |:.|.......||.|::|||.:||             .|.|       .||..:.||:
  Fly   197 TSNGISLGLKRSGAESPASPNSNSSSSAAASPIRPQRVPAMLQHPGLHLGHLAAAAASGFAASPS 261

  Fly   385 -----HSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPV 444
                 :.:..|.|                :.|:.:|.:...||...:.   |...|.||.|:.|.
  Fly   262 DFLVAYPNFYPNY----------------MHAAAVAHVAAAQMQAHVS---GAAAGLSGHGHHPH 307

  Fly   445 GVGGN-GSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNF 508
            ...|: ..|.:|              |...|..|.:.:|.|           .........||.|
  Fly   308 HPHGHPHHPHLG--------------AHHHGQHHLSHLGHG-----------PPPKRKRRHRTIF 347

  Fly   509 TNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQH 573
            |.:||.:||..|....|.....|.::|..:.|.|.:|::||:|||.|.:|:.:|
  Fly   348 TEEQLEQLEATFDKTHYPDVVLREQLALKVDLKEERVEVWFKNRRAKWRKQKRE----------- 401

  Fly   574 STSVISEKPPQQQQPQPPELQLKSQGSDLGG--NELATGAPSTPTTAMTLTAPTS 626
                        :|.:..:||.:..||...|  |..:....||...::|:..|.|
  Fly   402 ------------EQERLRKLQEEQCGSTTNGTTNSSSGTTSSTGNGSLTVKCPGS 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	21/52 (40%)
Gsc	NP_001137762.2	Homeodomain	341..397	CDD:459649	21/55 (38%)