Protein Alignment lab and CG32532

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Alignment Length: 696
• Identity: 165/696 - (23%)
• Similarity: 221/696 - (31%)
• Gaps: 284/696 - (40%)

  Fly   136 NPGTPLH--------PSSHSPADSY---YESDSVHSYYAT------------------------- 164
            :|..|.|        ..:.||.||:   |..|...:|..|
  Fly    16 SPKAPSHRHKIRSIKTGARSPRDSFQLDYSIDFFKTYIDTQRFYAGHKLDFKHQSCAGGPGSGGA 80

  Fly   165 -----------AAVATVAPPSNSSPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPTA 218
                       :.|..|...|||:...||........||||||.......|....:|      :|
  Fly    81 GGPGPGGGGGASGVVVVGGTSNSNNPAAAQQQQQQQQQQQQQQQQQSGGNNPSNGSN------SA 139

  Fly   219 QAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMDSL 283
            .|.:..|.:|           |||:|                      |..|..||:|    .:|
  Fly   140 VALSLAHPHA-----------HASHA----------------------HSSHAHGSHA----HAL 167

  Fly   284 GMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQQQQP----------------HQQPQHPQNQSPA 332
            .: ||.||||    |.::.....|||.|.||||||.                .||.|..|.|...
  Fly   168 AI-AHGHHGL----LPSVVPQQQQQQQQQQQQQQQQQQAQQLPPGVGVASPLQQQQQQQQQQQQQ 227

  Fly   333 AHQQHHQNSVSPNGGMNRQQ-----RGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTY 392
            ..||..|..:..|||::...     ..|..|.|:.|.|.::|:..|..|:..|.|   |||:|..
  Fly   228 QQQQQQQQQLINNGGVSAGTPTLLIGNGPSSSGAGTGSVSAAAAAAAAAAAASSS---SSSLPHV 289

  Fly   393 KWMQLKRNVPKPQAP-KLPASGIASMHDYQMN-------GQLDMCRGGGGGGSGVG-------NG 442
                         || .|..|..:|....|.|       .||:...||.||...:.       .|
  Fly   290 -------------APHSLGLSPQSSADSQQFNIFPAIFSRQLNFSAGGQGGKLSMDELRPNLVGG 341

  Fly   443 PVGV-------------GGNGSP------------GIGG-----VLSVQNSL------------- 464
            .:|:             ||.|..            ||||     :||:.:|:
  Fly   342 LLGLQQGLLEDHASMQHGGVGQDTKFMSFQDQRLMGIGGSHENRLLSLASSVQDTRSPITTLEKS 406

  Fly   465 ---------------------------------------------------IMANSAAAAGSAHP 478
                                                               |.|..|.......|
  Fly   407 SSSSLNHQRKCSSTPEDFSALYSGLPTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKPEP 471

  Fly   479 NG----MGVGLGS-GSGLSS-----------CSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLT 527
            |.    :..|:.| ||||||           .|..:......||.||.:||.|||..|..:.|..
  Fly   472 NSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCPTPARRRHRTTFTQEQLAELEAAFAKSHYPD 536

  Fly   528 RARRIEIANTLQLNETQVKIWFQNRR---MKQKKRVKEGLIPADI---------LTQHSTSVISE 580
            ...|.|:|.|.:|||.::::||||||   .||:|::::.|.|:.|         :..:|.|
  Fly   537 IYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVIPSCNGMMRNIQGYSVS---- 597

  Fly   581 KPPQQQQPQPPELQLKSQGSDLGGNELATGAPSTPTTAMTLTAPTS 626
               :..||.|....:.....||    ...||.|.|    .:|.|.|
  Fly   598 ---RGYQPYPHHNTMNRYPQDL----FQMGASSYP----GMTQPFS 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	26/55 (47%)
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	24/55 (44%)