Protein Alignment lab and B-H1

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_523387.1
• Gene: B-H1 / 32724
• FlyBaseID: FBgn0011758
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 126/562 - (22%)
• Similarity: 176/562 - (31%)
• Gaps: 232/562 - (41%)

  Fly    27 TTTASAANASSYFAPQQHQPHLQLQQQQQHQHLQQPQQHLTYNGYESSSPGNYYPQQQAQLTPPP 91
            |.|.|..||:.   ||.|. ||...|||.|||      ||.|.                  ..||
  Fly     9 TQTPSEPNAAH---PQLHH-HLSTLQQQHHQH------HLHYG------------------LQPP 45

  Fly    92 TSSHQVVQQHQQQQQAQQQQLYPHSHLFSPSAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESD 156
            ..:|.:                 ||            ||:.::|.
  Fly    46 AVAHSI-----------------HS------------TTTMSSGG-------------------- 61

  Fly   157 SVHSYYATAAVATVAPPSNS----SPITAANASATSNTQQQQQQAAIISSENGMMYTNLDCMYPT 217
                  :|...:.:..|:.|    :.|.|.:|:|....|||..|.        :.:.|.:....:
  Fly    62 ------STTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQ--------LHHHNNNNNSGS 112

  Fly   218 AQAQAPVHGYAGQIEEKYAAVLHASYAPGM-VLEDQDPMMQQATQSQMWHHQQHLAGSYALDAMD 281
            :...:|.|  :............||...|: ||           .|.:.|.|.|..
  Fly   113 SGGSSPAH--SNNNNNINGDNCEASNVAGVGVL-----------PSALHHPQPHPP--------- 155

  Fly   282 SLGMHAHMH-HGL--PHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHPQN-----QSPAAHQQHH 338
               .|.|.| |.|  |||.||                    |..|....|     |..||.|||:
  Fly   156 ---THPHTHPHALMHPHGKLG--------------------HFPPTAGGNGLNVAQYAAAMQQHY 197

  Fly   339 QNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPK 403
                                  ::.:::.:|.|.|..|:.
  Fly   198 ----------------------AAAAAAAAARNNAAAAAA------------------------- 215

  Fly   404 PQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMAN 468
             .|....|:|:|:       ..:|   ||..||.|:           :|..||.|...:.....|
  Fly   216 -AAAAAAAAGVAA-------PPVD---GGVDGGVGL-----------APPAGGDLDDSSDYHEEN 258

  Fly   469 -----------SAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHF 522
                       |..:.|....:|..|..||.|.:|..   |......||.||:.||..|||.|..
  Fly   259 EDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGL---SKKQRKARTAFTDHQLQTLEKSFER 320

  Fly   523 NRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGL 564
            .:||:...|.|:|:.|.|::.|||.|:||||.|.|::...||
  Fly   321 QKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGL 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	26/52 (50%)
B-H1	NP_523387.1	Homeodomain	300..356	CDD:459649	26/55 (47%)