Protein Alignment lab and HOXD1

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 96/284 - (33%)
• Similarity: 121/284 - (42%)
• Gaps: 50/284 - (17%)

  Fly   354 GGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASG----- 413
            |..:|.....::..|.|..|.||......|    :.|.|....|:.......||...|.|
Human    48 GAFVSCLPLAAARPSPSPPAAPARPSVPPP----AAPQYAQCTLEGAYEPGAAPAAAAGGADYGF 108

  Fly   414 IASMHDYQMNGQLDMCRGGG-------------GGGSGVGNGPVGVGGNGSPG-IGGVL--SVQN 462
            :.|...|...|.|......|             ||||.:.:|.|.....|.|| ....|  |...
Human   109 LGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADG 173

  Fly   463 SLIMANSAAAAGSAHPNGMGVGLGSGSGLSS---CSLSSNTNNSG--------------RTNFTN 510
            ......:|:.|...:|..:....|..:..|:   ..:..|.:..|              ||||:.
Human   174 HPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFST 238

  Fly   511 KQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADI------ 569
            |||||||||||||:||||||||||||.|.||:|||||||||||||||||.:|||:...|
Human   239 KQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQ 303

  Fly   570 --LTQHSTSVISEKPPQQQQPQPP 591
              |:..:.:...:.|....|.|.|
Human   304 LPLSGTTPTKFIKNPGSPSQSQEP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	45/51 (88%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeobox	233..285	CDD:278475	45/51 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		5/23 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41441
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45946
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2567
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030