Protein Alignment lab and HOXB8

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 73/270 - (27%)
• Similarity: 96/270 - (35%)
• Gaps: 97/270 - (35%)

  Fly   351 QQRGG----VISPGSSTSSSTSASNGAHPASTQS--KSPNHSSSIPTYKWMQLKRNVPKPQAPKL 409
            |..||    |..|.|..|..       ||:..|.  ..|:..|:.|
Human    30 QDLGGRPTVVYGPSSGGSFQ-------HPSQIQEFYHGPSSLSTAP------------------- 68

  Fly   410 PASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPG-IGGVLSVQNSLIMANSAAAA 473
                      ||.|                   |..|..:|.|| ..|...:|...:.
Human    69 ----------YQQN-------------------PCAVACHGDPGNFYGYDPLQRQSLF------- 97

  Fly   474 GSAHPNGMGVG---LGSGSGLSSCSLSSNTNNS------------------GRTNFTNKQLTELE 517
            |:..|:.:...   |.:.|||...:..|..:.|                  ||..::..|..|||
Human    98 GAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELE 162

  Fly   518 KEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKP 582
            |||.||.||||.||||:::.|.|.|.||||||||||||.||...:...|       |:....|:.
Human   163 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFP-------SSKCEQEEL 220

  Fly   583 PQQQQPQPPE 592
            .:|:..:.||
Human   221 EKQKLERAPE 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	33/51 (65%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeobox	150..203	CDD:395001	33/52 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810