Protein Alignment lab and HOXB6

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 84/318 - (26%)
• Similarity: 119/318 - (37%)
• Gaps: 75/318 - (23%)

  Fly   316 QQQPHQQPQHPQNQSPAAHQQHHQNSVSPNG------GMNRQQRGG-----VISPGSS------- 362
            ::.|......|:|...:.|.:..:    |..      |.|..:|..     :|:|...
Human     2 RETPPSPGSLPENAQVSRHSRRRE----PRSTGRQFCGFNAARRSDYKTQQIINPAEQQRPRAPP 62

  Fly   363 TSSSTSASNGAHPASTQSKSPNHSSSIPTYK--WMQLKRNVPKPQAPKLPA--SGIASMHDYQMN 423
            ...|:...|...|.:..|...:....:|.|.  :....|:.|.|..|. |.  .|.|:...|...
Human    63 LPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPG-PGQDKGFATSSYYPPA 126

  Fly   424 GQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSG 488
            |      ||.|..:....||       :|..   ...:.|....:.|......||..........
Human   127 G------GGYGRAAPCDYGP-------APAF---YREKESACALSGADEQPPFHPEPRKSDCAQD 175

  Fly   489 SG--------------------LSSCSLSS--NTNNSGRTNFTNKQLTELEKEFHFNRYLTRARR 531
            ..                    ::||:.||  .:...||..:|..|..|||||||:||||||.||
Human   176 KSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRR 240

  Fly   532 IEIANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQ 589
            ||||:.|.|.|.|:||||||||||.||..|       :|   |.|.:|.:..:::|.:
Human   241 IEIAHALCLTERQIKIWFQNRRMKWKKESK-------LL---SASQLSAEEEEEKQAE 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	36/51 (71%)
HOXB6	XP_011523029.1	Homeobox	214..266	CDD:278475	36/51 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810