Protein Alignment lab and HOXB5

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 79/314 - (25%)
• Similarity: 112/314 - (35%)
• Gaps: 118/314 - (37%)

  Fly   271 LAGSYALDAMDSLGMHAHMHHGL---------PHGHLGNLANNPHQQQPQVQQQQQQPHQQPQHP 326
            |:|||...|....|.:.:.::|:         ...|.|.:..:        .:....|.|:|:..
Human    30 LSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGES--------SRAFPAPAQEPRFR 86

  Fly   327 QNQSPAAHQQHHQNSVSPNG--GMNRQQRGGVISPGSSTSSSTSASNGAH--------------P 375
            |..|..:..       ||..  ..|....|...|..|.:..:||||:.|:              .
Human    87 QAASSCSLS-------SPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEE 144

  Fly   376 ASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMH-DYQMNGQLDMCRGGGGGGSGV 439
            |::|..||:.:.:.|  :.|......|:.|.|:: ...:..:| .:.|.|
Human   145 AASQLSSPSLARAQP--EPMATSTAAPEGQTPQI-FPWMRKLHISHDMTG--------------- 191

  Fly   440 GNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSG 504
                                                  |:|                     ...
Human   192 --------------------------------------PDG---------------------KRA 197

  Fly   505 RTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKK 558
            ||.:|..|..||||||||||||||.||||||:.|.|:|.|:||||||||||.||
Human   198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	38/51 (75%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	24/120 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		23/104 (22%)
		Antp-type hexapeptide	176..181		0/5 (0%)
		Homeobox	198..251	CDD:395001	38/52 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810