Protein Alignment lab and HOXB4

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 66/242 - (27%)
• Similarity: 83/242 - (34%)
• Gaps: 103/242 - (42%)

  Fly   319 PHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSP 383
            |...|..|...||.|.......::.|..|    ||...:|  ||......|.|..||      ||
Human    79 PPPPPPPPPGLSPRAPAPPPAGALLPEPG----QRCEAVS--SSPPPPPCAQNPLHP------SP 131

  Fly   384 NHSS--SIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGV 446
            :||:  ....|.||:                   .:|
Human   132 SHSACKEPVVYPWMR-------------------KVH---------------------------- 149

  Fly   447 GGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNK 511
                                      ..:.:||..|                ......||.:|.:
Human   150 --------------------------VSTVNPNYAG----------------GEPKRSRTAYTRQ 172

  Fly   512 QLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKK 558
            |:.|||||||:||||||.||:|||:.|.|:|.|:||||||||||.||
Human   173 QVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKK 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	36/51 (71%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		19/66 (29%)
		Antp-type hexapeptide	141..146		2/4 (50%)
		Homeobox	165..218	CDD:278475	36/52 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		66/242 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810