Protein Alignment lab and HOXA5

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 88/327 - (26%)
• Similarity: 112/327 - (34%)
• Gaps: 119/327 - (36%)

  Fly   251 DQDPMMQQATQSQMWHHQQHLAGSYALDAMD-SLGMHAHMHHGLPHGHLGNLANN---------- 304
            |...:.:|...|...|..::   .|..:.|| |:|.....|.|     .|..|.:
Human    26 DHSSVSEQFRDSASMHSGRY---GYGYNGMDLSVGRSGSGHFG-----SGERARSYAASASAAPA 82

  Fly   305 -PHQQQPQVQQQQQQPHQQPQHPQNQSPAAHQQHH--QNSVSPNGGMNRQQRGGVISPGSSTSSS 366
             |...||.......||...|......||.: ..||  :||:|.:.|.:.......||......::
Human    83 EPRYSQPATSTHSPQPDPLPCSAVAPSPGS-DSHHGGKNSLSNSSGASADAGSTHISSREGVGTA 146

  Fly   367 TSASNGAHPASTQSKSPNHSSSIP-----TYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQL 426
            :.|...|..:|.|:.:.:..|..|     .|.||:           ||..|     ||
Human   147 SGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMR-----------KLHIS-----HD------- 188

  Fly   427 DMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGL 491
                                      .|||                     |.|
Human   189 --------------------------NIGG---------------------PEG----------- 195

  Fly   492 SSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQ 556
                      ...||.:|..|..||||||||||||||.||||||:.|.|:|.|:||||||||||.
Human   196 ----------KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 250

  Fly   557 KK 558
            ||
Human   251 KK 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	38/51 (75%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		22/100 (22%)
		Antp-type hexapeptide	176..181		2/4 (50%)
		Homeobox	199..251	CDD:306543	38/51 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810