Protein Alignment lab and Vsx1

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001284898.1
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 150/673 - (22%)
• Similarity: 212/673 - (31%)
• Gaps: 277/673 - (41%)

  Fly    63 QQHLTYNGYESSSPGNYYPQQQAQLTPPPTS------SHQVVQQHQQQQQAQQQQLYPHSHLFSP 121
            ||..|.:...|.:|    |...|  |||||:      |...|||.|||||.||||
  Fly    22 QQQATASATPSEAP----PSPAA--TPPPTANTPANGSLSAVQQQQQQQQQQQQQ---------- 70

  Fly   122 SAAEYGITTSTTTGNPGTPLHPSSHSPADSYYESDSVHSYYATAAVATVAPP-SNSSPITAANAS 185
                            ...|........||..||.|            ::|. |..|...||.|:
  Fly    71 ----------------QQQLQQQQQQAIDSLRESRS------------ISPDVSRLSAAAAAAAA 107

  Fly   186 ATSNTQQQQQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLE 250
            |.::.     |..:.:..|         .|..|       |||...:...||..|
  Fly   108 AAAHC-----QLPVFNPAN---------FYAAA-------GYAAAADPGNAAAAH---------- 141

  Fly   251 DQDPMMQQATQSQMWHHQQHLAGSYALDAMDSLGMHAHMHHGLPHGHLGNLANNPHQQQPQVQQQ 315
                           ||.           |.:|...|::...||.|.     :.||:.:...||
  Fly   142 ---------------HHH-----------MTTLAAAAYLRGFLPPGF-----STPHEFRGHFQQ- 174

  Fly   316 QQQPHQQPQHPQNQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQS 380
                |...|..  :..||..|.:.:|::...|..:       ||..::|||.:..:|...:.:..
  Fly   175 ----HFGAQFA--EQAAARGQEYASSLANASGDEQ-------SPSKNSSSSGNGGSGGSGSGSGG 226

  Fly   381 KSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVG 445
            .:|.                          ::|:..:      |......||.|||:|||....|
  Fly   227 GNPT--------------------------SNGLGHL------GSPTASNGGSGGGAGVGGSGGG 259

  Fly   446 VGGNGS----PGIGG----------VLSVQNSLIMA---NSAAAAGSAHPNGMG----------- 482
            .|.:||    .|.||          .....:|..:|   ::||||.:||.:...
  Fly   260 SGTSGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAAAAAAHHHAAAAAAAHHAHHAH 324

  Fly   483 --------------------------------VGLGSGSGLSSCSL------------------- 496
                                            :|...|:|.:..||
  Fly   325 AQAHAHAHAHVHAHAAHAAHAAHAHAHHAEAFLGAAGGAGGNPNSLLAAHGGDVLVGPGGTGPGG 389

  Fly   497 -SSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRV 560
             ..|....|||.||:.||.||||.|....|...:.|..::....|.|.::::|:||||.|.:|..
  Fly   390 KKKNKRRHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRKTE 454

  Fly   561 K----------EGLIPADILTQHS-----TSVISEKPPQQQQP----------QPPELQLKSQGS 600
            |          .||..|  :.:||     |.:.|.|..:...|          :..|| |||..|
  Fly   455 KCWGHSTKMAEYGLYGA--MVRHSLPLPETIIKSAKEDESVAPWLLGMHKKSLEAAEL-LKSDES 516

  Fly   601 DLGGNELATGAPSTPTTAMTLTA 623
            |          ..|||:..|.|:
  Fly   517 D----------RETPTSDDTNTS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	21/51 (41%)
Vsx1	NP_001284898.1	Homeobox	399..451	CDD:278475	21/51 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I3555
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	59	1.000	Inparanoid score	I4021
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.050