Protein Alignment lab and Vsx2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 118/566 - (20%)
• Similarity: 164/566 - (28%)
• Gaps: 245/566 - (43%)

  Fly   138 GTPLHPSSHSPADSYYESDSVHSYYATAAVATVA-------PP--SNSSPITAANASATSNTQQQ 193
            |..:..::.:|.|           ..|.|.||||       ||  :|::..|||.::||:.|
  Fly    14 GLAVAAATEAPTD-----------LTTTAGATVAKERQTPTPPKTTNATMATAATSAATAAT--- 64

  Fly   194 QQQAAIISSENGMMYTNLDCMYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQ 258
                                  ||..|:    |....:.|                ..|.|..||
  Fly    65 ----------------------PTNAAE----GNLTSVSE----------------PQQQPQQQQ 87

  Fly   259 ATQS--QMWHHQ---QHLAGSYALDAMDSLGMHAHMHHG-LPHGHLGNLANNPHQQQPQVQQQQQ 317
            ..|.  |..|||   .|.....|...|.....||.:... :|| .|....::.||     .|.|.
  Fly    88 QEQQHHQPHHHQYREHHQMTMAAASRMAYFNAHAAVAAAFMPH-QLAAAVHHHHQ-----HQHQH 146

  Fly   318 QPHQQPQHPQ----NQSPAAHQQHHQNSVSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPAST 378
            .||..|.||.    ...|....|||.
  Fly   147 HPHHHPHHPHGAVGGPPPPPPMQHHH--------------------------------------- 172

  Fly   379 QSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGP 443
                |:|                  |..|.|.|.|...:..:               .:|.|
  Fly   173 ----PHH------------------PHHPLLHAQGFPQLKSF---------------AAGAG--- 197

  Fly   444 VGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNF 508
            ..:.|:.:|...|:.|:                  ||.|||..|       ..........||.|
  Fly   198 TCLPGSLAPKDFGMESL------------------NGFGVGPNS-------KKKKKKRRHSRTIF 237

  Fly   509 TNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNRRMKQKKRVK----------EG 563
            |:.||.:||:.|....|.....|..::...:|.|.::::||||||.|.:|..|          .|
  Fly   238 TSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAEYG 302

  Fly   564 LIPADILTQHS-----TSVISEKPPQQQQPQPPELQLK-------------------SQGSDLGG 604
            |..|  :.:||     |.:.|.|......|....::.|                   |...|..|
  Fly   303 LYGA--MVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDSAG 365

  Fly   605 NELA-----------------------TGAPST-PTTAMTLTAPTS 626
            ::.|                       :.|||: ||:|.|...|||
  Fly   366 SKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPPTS 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	20/52 (38%)
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	20/56 (36%)
		OAR	556..572	CDD:461067