Protein Alignment lab and msx2b

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_571351.3
• Gene: msx2b / 30531
• ZFINID: ZDB-GENE-980526-492
• Length: 241
• Species: Danio rerio
• Alignment Length: 277
• Identity: 72/277 - (25%)
• Similarity: 101/277 - (36%)
• Gaps: 79/277 - (28%)

  Fly   362 STSSSTSASNG------------AHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGI 414
            |.|:|...|:|            :||.|.:|...:|.    |.|..:.:|.....|
Zfish     2 SASASLKESDGDRDMEQRKTQVSSHPFSVESLISSHK----TNKDFERRREDVSSQ--------- 53

  Fly   415 ASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHPN 479
                 :......|.|                    ||.||.....:|.|.:.:.      |..|:
Zfish    54 -----FAQTEIRDSC--------------------GSAGIPKHFMLQTSPVKSE------SPEPD 87

  Fly   480 G-----MGVGLGSGSGLSSCSLSSN-TNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTL 538
            .     |..........|.|.|..: ||...||.||..||..||::|...:||:.|.|.|.:::|
Zfish    88 DCTSWVMNSRYSQTRQESPCPLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSL 152

  Fly   539 QLNETQVKIWFQNRRMKQKKRVKEGL----------------IPADILTQ-HSTSVISEKPPQQQ 586
            .|.||||||||||||.|.|:..:..|                :|..:.|| ||...:..:....|
Zfish   153 TLTETQVKIWFQNRRAKAKRLQEAELEKLKLTAKPALHPNFSLPLPLGTQLHSAVSLYGQSYPYQ 217

  Fly   587 QPQPPELQLKSQGSDLG 603
            :|..|...:...|:.||
Zfish   218 RPLLPVAPVGLYGTPLG 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	29/52 (56%)
msx2b	NP_571351.3	Homeodomain	116..172	CDD:459649	29/55 (53%)