DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lab and hoxc5a

DIOPT Version :9

Sequence 1:	NP_476613.1	Gene:	lab / 40817	FlyBaseID:	FBgn0002522	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_571219.2	Gene:	hoxc5a / 30379	ZFINID:	ZDB-GENE-980526-533	Length:	233	Species:	Danio rerio

Alignment Length:	235	Identity:	78/235 - (33%)
Similarity:	98/235 - (41%)	Gaps:	49/235 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 SSTSSSTSASNGAHPASTQSK--------SPNHSSSIPTYKWMQLKRN-------------VPKP 404
            ||....|..:.|||....:|.        ..:.||.|||   ..|:|.             |.:.
Zfish    17 SSCRMHTFDNYGAHSEFHESNYAYEGLDLGGSFSSQIPT---NSLRREAINTTDRARSSAAVQRT 78

  Fly   405 QA-PKLPASGIASMHDYQ--MNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLI- 465
            |: ..|.:....|.|.|.  .:|.|..        ...||..|....:|......:.....|.|
Zfish    79 QSCSALGSRSFVSTHGYNPLSHGLLSQ--------KAEGNMEVMEKPSGKSRTDDIKMETTSAIK 135

  Fly   466 -MANSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNS-GRTNFTNKQLTELEKEFHFNRYLTR 528
             ..||......:.|.       ....::...:|..::.. .||::|..|..||||||||||||||
Zfish   136 QQTNSTQRQNQSQPQ-------IYPWMTKLHMSHESDGKRSRTSYTRYQTLELEKEFHFNRYLTR 193

  Fly   529 ARRIEIANTLQLNETQVKIWFQNRRMKQKK----RVKEGL 564
            .|||||||.|.|||.|:||||||||||.||    :||.||
Zfish   194 RRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKLKVKGGL 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	40/51 (78%)
hoxc5a	NP_571219.2	Homeobox	169..222	CDD:278475	40/52 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000