Protein Alignment lab and hoxb4a

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_571193.1
• Gene: hoxb4a / 30340
• ZFINID: ZDB-GENE-990415-105
• Length: 246
• Species: Danio rerio
• Alignment Length: 314
• Identity: 78/314 - (24%)
• Similarity: 110/314 - (35%)
• Gaps: 125/314 - (39%)

  Fly   311 QVQQQQQQPHQQPQH--PQNQSPAAHQQ--HHQNSVSPNGGMNRQQRGG----VISPGS----ST 363
            :..|....|...|.:  .|.|.|:...:  :||.|...:...:..|..|    ||||..    :|
Zfish    22 EYSQSDYLPSHSPDYYSAQRQDPSFQHESIYHQRSGCADPPYSSCQGPGQPAAVISPRGHVLPTT 86

  Fly   364 SSSTSASNGAH----------PASTQSKSPNHSSSIPT------YKWMQLKRNVPKPQAPKLPAS 412
            :.||.....:|          ||..|:.:..::|::.:      |.||:
Zfish    87 ALSTPLPEPSHHCDSVTPSPPPACGQTPTSQNTSTVSSRKDPVVYPWMK---------------- 135

  Fly   413 GIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAH 477
                                                                          ..|
Zfish   136 --------------------------------------------------------------KVH 138

  Fly   478 PNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNE 542
            .|           :.|.:.|.......||.:|.:|:.|||||||:||||||.||:|||:||.|:|
Zfish   139 VN-----------IVSPNYSGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHTLCLSE 192

  Fly   543 TQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPP-----QQQQPQPP 591
            .|:||||||||||.||..|   :|...:..:|.|..|...|     |.:...||
Zfish   193 RQIKIWFQNRRMKWKKDHK---LPNTKIRSNSASTNSSGCPTLCSNQSRASGPP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxb4a	NP_571193.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..125		23/101 (23%)
		Antp-type hexapeptide	130..135		2/4 (50%)
		Homeodomain	152..208	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..246		9/37 (24%)