Protein Alignment lab and hoxa2b

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_571181.1
• Gene: hoxa2b / 30325
• ZFINID: ZDB-GENE-990415-98
• Length: 363
• Species: Danio rerio
• Alignment Length: 323
• Identity: 84/323 - (26%)
• Similarity: 114/323 - (35%)
• Gaps: 125/323 - (38%)

  Fly   361 SSTSSST----------------SASNGAHPASTQSK-SPNHSSSIPT------YKWMQLKRNVP 402
            ||..|||                |.:.|:||..::.| :||.|..:|.      |.||:.|:...
Zfish    35 SSIKSSTLSHSTLIPPPFEQTIPSLNPGSHPRHSRPKQNPNGSCPLPAASLPPEYPWMKEKKASK 99

  Fly   403 KPQAPKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMA 467
            |.|.....|:                          ...||:.....|||.|.
Zfish   100 KNQTTSTAAT--------------------------TDPGPLYFSPQGSPEIS------------ 126

  Fly   468 NSAAAAGSAHPNGMGVGLGSGSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRI 532
                              ..|||         .....||.:||.||.|||||||||:||.|.||:
Zfish   127 ------------------DGGSG---------ATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 164

  Fly   533 EIANTLQLNETQVKIWFQNRRMKQKKRVK-------EGLIPA--------------DILTQHSTS 576
            |||..|.|.|.|||:||||||||.|::.:       :|..|:              :.:..:.:.
Zfish   165 EIAALLDLTERQVKVWFQNRRMKHKRQTQCKENHHGDGKPPSLEEAGGRGDGKSFFEQVANNVSG 229

  Fly   577 VISEKP--PQQQQPQPPELQLKSQGSD--------LGGNE-----LATGAPSTPTTAMTLTAP 624
            .:.|:.  |.||.....:.......||        ||.|:     ....:|:.|....|: ||
Zfish   230 ALLEREGYPFQQNTLTSQQSQNGHNSDSQSATVSPLGSNDKHLKHFPNPSPTVPICTTTM-AP 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	37/52 (71%)
hoxa2b	NP_571181.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..132		25/154 (16%)
		Antp-type hexapeptide	88..93		2/4 (50%)
		Homeodomain	134..190	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..218		5/31 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..279		5/33 (15%)