Protein Alignment lab and Meox2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_058845.2
• Gene: Meox2 / 29279
• RGDID: 3079
• Length: 303
• Species: Rattus norvegicus
• Alignment Length: 421
• Identity: 106/421 - (25%)
• Similarity: 139/421 - (33%)
• Gaps: 150/421 - (35%)

  Fly   214 MYPTAQAQAPVHGYAGQIEEKYAAVLHASYAPGMVLEDQDPMMQQATQSQMWHHQQHLAGSYALD 278
            ::|.:|:...:||.:.          |.||          |.:..::.|.:      :|| |.
  Rat    19 LHPFSQSSLALHGRSD----------HMSY----------PELSTSSSSCI------IAG-YP-- 54

  Fly   279 AMDSLGMHAHMHH-GLPHGHLGNLANNPHQQQPQVQQQQQQPHQQPQH-PQNQSPAAHQQHHQNS 341
              :..||.|..|| |..|.|        |......||||.|..|...| ||..||.: ...|...
  Rat    55 --NEEGMFASQHHRGHHHHH--------HHHHHHHQQQQHQALQSNWHLPQMSSPPS-AARHSLC 108

  Fly   342 VSPNGGMNRQQRGGVISPGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQA 406
            :.|:.       ||....|||            |....|.|.:..||.||
  Rat   109 LQPDS-------GGPPELGSS------------PPVLCSNSSSLGSSTPT--------------- 139

  Fly   407 PKLPASGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAA 471
                                                    |...:||..|    :.:|..|....
  Rat   140 ----------------------------------------GAACAPGDYG----RQALSPAEVEK 160

  Fly   472 AAGSAHPNGMGVGLGSGSGLSSCSLSSNTNN---SGRTNFTNKQLTELEKEFHFNRYLTRARRIE 533
            .:||...:       ..|.....:..|..|:   ..||.||.:|:.|||.||..:.||||.||.|
  Rat   161 RSGSKRKS-------DSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYE 218

  Fly   534 IANTLQLNETQVKIWFQNRRMKQKKRVKEGLIPADILTQHSTSVISEKPPQQQQPQPPELQLKSQ 598
            ||..|.|.|.|||:||||||||. ||||.|                   .|....:..||....:
  Rat   219 IAVNLDLTERQVKVWFQNRRMKW-KRVKGG-------------------QQGAAAREKELVNVKK 263

  Fly   599 GSDLGGNELATGAPSTPTTAMTLTAPTSKQS 629
            |:.|.......||.:...|..:|....|:.|
  Rat   264 GTLLPSELSGIGAATLQQTGDSLANDDSRDS 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	33/52 (63%)
Meox2	NP_058845.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..191		42/221 (19%)
		Homeodomain	187..243	CDD:459649	33/56 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	279..303		4/16 (25%)