Protein Alignment lab and Pdx1

DIOPT Version :9

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 279
• Identity: 75/279 - (26%)
• Similarity: 101/279 - (36%)
• Gaps: 95/279 - (34%)

  Fly   359 PGSSTSSSTSASNGAHPASTQSKSPNHSSSIPTYKWMQLKRNVPKPQAPKLPASGIASMHDYQMN 423
            |...|||..|...|:.|            .|..|:       || |.|...||.  |.:| :.:.
Mouse    47 PPQFTSSLGSLEQGSPP------------DISPYE-------VP-PLASDDPAG--AHLH-HHLP 88

  Fly   424 GQLDMCRGGGGGGSGVGNGPVGVGGNGSPGIGGVLSVQNSLIMANSAAAAGSAHP-NGMGVGLGS 487
            .||           |:.:.|.|...||:.  .|.|...|.:.:......:..||. .|...|
Mouse    89 AQL-----------GLAHPPPGPFPNGTE--PGGLEEPNRVQLPFPWMKSTKAHAWKGQWAG--- 137

  Fly   488 GSGLSSCSLSSNTNNSGRTNFTNKQLTELEKEFHFNRYLTRARRIEIANTLQLNETQVKIWFQNR 552
                .:.:.....|...||.:|..||.||||||.||:|::|.||:|:|..|.|.|..:|||||||
Mouse   138 ----GAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNR 198

  Fly   553 RMKQKKR---------------------------------------------------VKEGLIP 566
            |||.||.                                                   |:|||:|
Mouse   199 RMKWKKEEDKKRSSGTPSGGGGGEEPEQDCAVTSGEELLAVPPLPPPGGAVPPGVPAAVREGLLP 263

  Fly   567 ADILTQHSTSVISEKPPQQ 585
            :.:......|.|:...||:
Mouse   264 SGLSVSPQPSSIAPLRPQE 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeobox	505..557	CDD:278475	32/51 (63%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		11/45 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		27/104 (26%)
		Antp-type hexapeptide	119..124		0/4 (0%)
		Homeobox	150..203	CDD:278475	32/52 (62%)
		Nuclear localization signal	198..204		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		11/81 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900