Protein Alignment lab and Msx2

DIOPT Version :10

• Sequence 1: NP_476613.1
• Gene: lab / 40817
• FlyBaseID: FBgn0002522
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_038629.2
• Gene: Msx2 / 17702
• MGIID: 97169
• Length: 267
• Species: Mus musculus
• Alignment Length: 222
• Identity: 63/222 - (28%)
• Similarity: 88/222 - (39%)
• Gaps: 44/222 - (19%)

  Fly   353 RGGVISPGSSTSSSTSASNGAHPASTQSKSPNHS---SSIPTYKWMQLKRNVPKPQAPKLP---A 411
            :||.:........:..|..|..|...:..:....   ||:|......:....|..::|.:|   |
Mouse     6 KGGDLFSSDEEGPAVLAGPGPGPGGAEGSAEERRVKVSSLPFSVEALMSDKKPPKESPAVPPDCA 70

  Fly   412 SGIASMHDYQMNGQLDMCRGGGGGGSGVGNGPVGVGGNGSPG-------IGGVLSVQNSLIMANS 469
            |..|.:....:.|.                   ||....|||       ...|.| :||...|..
Mouse    71 SAGAVLRPLLLPGH-------------------GVRDAHSPGPLVKPFETASVKS-ENSEDGAPW 115

  Fly   470 AAAAG--SAHPNGMGVGLGSGSGLSSCSLSSN-TNNSGRTNFTNKQLTELEKEFHFNRYLTRARR 531
            ....|  |..|..|..        ::|:|..: ||...||.||..||..||::|...:||:.|.|
Mouse   116 IQEPGRYSPPPRHMSP--------TTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAER 172

  Fly   532 IEIANTLQLNETQVKIWFQNRRMKQKK 558
            .|.:::|.|.||||||||||||.|.|:
Mouse   173 AEFSSSLNLTETQVKIWFQNRRAKAKR 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lab	NP_476613.1	Homeodomain	505..558	CDD:459649	29/52 (56%)
Msx2	NP_038629.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		5/35 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..132		9/36 (25%)
		Homeodomain	143..199	CDD:459649	29/55 (53%)